Context Expectations play a central role in the mechanism of the placebo effect. In Parkinson
disease (PD), the placebo effect is associated with release of endogenous dopamine in …

The National Electrical Manufacturers Association (NEMA) standard NU 4-2008 for performance
measurements of small-animal tomographs was recently published. Before this standard…

Background People with Parkinson's disease can show premotor neurochemical changes
in the dopaminergic and non-dopaminergic systems. Using PET, we assessed whether …

Individual differences in dopamine (DA) signaling, including low striatal D 2/3 receptors,
may increase vulnerability to substance abuse, although whether this phenotype confers …

Background The objective of this study was to examine the effects of aerobic exercise on
evoked dopamine release and activity of the ventral striatum using positron emission …

With continuing improvements in spatial resolution of positron emission tomography (PET)
scanners, small patient movements during PET imaging become a significant source of …

Objective: In this prospective cohort study, we investigated cerebral glucose metabolism
reductions on [ 18 F]-fluorodeoxyglucose (FDG)-PET in progranulin (GRN) mutation carriers …

PET imaging of rodents is increasingly used in preclinical research, but its utility is limited by
spatial resolution and signal-to-noise ratio of the images. A recently developed preclinical …

Background and Objectives: To study selective regional binding for tau pathology in vivo,
using PET with [ 11 C]PBB3 in PSP patients, and other conditions not typically associated with …

Studies showed that the dopamine (DA) transporter (DAT) modulates changes in levodopa‐derived
synaptic dopamine levels (Δ(DA)) in Parkinson’s disease (PD). Here we evaluate …