Patients with glioblastoma multiforme (GBM), the most common primary brain tumor in adults,
have still a poor prognosis though new strategies of radio- and chemotherapy have been …

Background Mutations in SACS, leading to autosomal-recessive spastic ataxia of Charlevoix-Saguenay
(ARSACS), have been identified as a frequent cause of recessive early-onset …

Objective To generate high-resolution maps of the viscoelastic properties of human brain
parenchyma for presurgical quantitative assessment in glioblastoma (GB). Methods Twenty-…

Deep brain stimulation (DBS) of the internal globus pallidus (GPi) and ventral intermediate
thalamic nucleus (VIM) are established treatment options in primary dystonia and tremor …

The spectrum of neurodegenerative diseases covers the dementias, parkinsonian syndromes,
Huntington disease, amyotrophic lateral sclerosis, and prion diseases. In these entities, …

Mechanical properties of biological tissues and, above all, their solid or fluid behavior influence
the spread of malignant tumors. While it is known that solid tumors tend to have higher …

To date, limited data are available regarding the inter-site consistency of test–retest
reproducibility of functional connectivity measurements, in particular with regard to integrity of the …

Large-scale longitudinal neuroimaging studies with diffusion imaging techniques are necessary
to test and validate models of white matter neurophysiological processes that change in …

Age-related white matter hyperintensities (WMH) are a manifestation of white matter damage
seen on magnetic resonance imaging (MRI). They are related to vascular risk factors and …

Background and purpose Advanced imaging analysis for the prediction of tumor biology and
modelling of clinically relevant parameters using computed imaging features is part of the …