User profiles for Karine Dubé
Karine Dube, DrPHAssociate Professor ǀ UCSD School of Medicine Division of Infectious Diseases and Global … Verified email at health.ucsd.edu Cited by 2105 |
Applying the behavioural and social sciences research (BSSR) functional framework to HIV cure research
K Dubé, JD Auerbach, MJ Stirratt… - African Journal of …, 2019 - journals.lww.com
Introduction: The search for an HIV cure involves important behavioural and social processes
that complement the domains of biomedicine. However, the field has yet to tap into the full …
that complement the domains of biomedicine. However, the field has yet to tap into the full …
Participant perspectives in an HIV cure-related trial conducted exclusively in women in the United States: results from AIDS clinical trials group 5366
K Dubé, L Hosey, K Starr, L Barr, D Evans… - AIDS research and …, 2020 - liebertpub.com
Women remain underrepresented in HIV research. The AIDS Clinical Trials Group (ACTG)
5366 study was the first HIV cure-related trial conducted exclusively in women. Our …
5366 study was the first HIV cure-related trial conducted exclusively in women. Our …
[HTML][HTML] Willingness to participate and take risks in HIV cure research: survey results from 400 people living with HIV in the US
Introduction Participation in early-phase HIV cure studies includes clinical risks with little to
no likelihood of clinical benefit. Examining the willingness of people living with HIV to …
no likelihood of clinical benefit. Examining the willingness of people living with HIV to …
[HTML][HTML] Multi-stakeholder consensus on a target product profile for an HIV cure
Developing a cure for HIV is a global priority. Target product profiles are a tool commonly used
throughout the drug development process to align interested parties around a clear set of …
throughout the drug development process to align interested parties around a clear set of …
Recommendations for analytical antiretroviral treatment interruptions in HIV research trials—report of a consensus meeting
Analytical antiretroviral treatment interruption (ATI) is an important feature of HIV research,
seeking to achieve sustained viral suppression in the absence of antiretroviral therapy (ART) …
seeking to achieve sustained viral suppression in the absence of antiretroviral therapy (ART) …
[HTML][HTML] 'Well, it's the risk of the unknown… right?': a qualitative study of perceived risks and benefits of HIV cure research in the United States
K Dubé, J Taylor, L Sylla, D Evans, L Dee, A Burton… - PloS one, 2017 - journals.plos.org
Introduction Biomedical research towards an HIV cure is advancing in the United States and
elsewhere, yet little is known about perceptions of risks and benefits among potential study …
elsewhere, yet little is known about perceptions of risks and benefits among potential study …
Towards multidisciplinary HIV-cure research: integrating social science with biomedical research
…, AL Ross, JD Auerbach, J Ananworanich, K Dubé… - Trends in …, 2016 - cell.com
The quest for a cure for HIV remains a timely and key challenge for the HIV research community.
Despite significant scientific advances, current HIV therapy regimens do not completely …
Despite significant scientific advances, current HIV therapy regimens do not completely …
How does the timing of antiretroviral therapy initiation in acute infection affect HIV reservoirs?
J Ananworanich, K Dubé… - Current Opinion in HIV and …, 2015 - journals.lww.com
It is clear that early ART has a greater impact in limiting the HIV reservoirs than later treatment.
However, latently infected long-lived memory CD4+ T cells persist in most early treated …
However, latently infected long-lived memory CD4+ T cells persist in most early treated …
“We need to deploy them very thoughtfully and carefully”: Perceptions of analytical treatment interruptions in HIV cure research in the United States—A qualitative …
K Dubé, D Evans, L Dee, L Sylla, J Taylor… - AIDS Research and …, 2018 - liebertpub.com
Strategies to control HIV in the absence of antiretroviral therapy are needed to cure HIV.
However, such strategies will require analytical treatment interruptions (ATIs) to determine their …
However, such strategies will require analytical treatment interruptions (ATIs) to determine their …
[HTML][HTML] Interrupting antiretroviral treatment in HIV cure research: scientific and ethical considerations
Over the past several years there has been intense activity directed at the possibility of
achieving remission or eradication of HIV infection. Current assays for the measurement of latent …
achieving remission or eradication of HIV infection. Current assays for the measurement of latent …