User profiles for Karine Dubé

Karine Dube, DrPH

Associate Professor ǀ UCSD School of Medicine Division of Infectious Diseases and Global …
Verified email at health.ucsd.edu
Cited by 2105

Applying the behavioural and social sciences research (BSSR) functional framework to HIV cure research

K Dubé, JD Auerbach, MJ Stirratt… - African Journal of …, 2019 - journals.lww.com
Introduction: The search for an HIV cure involves important behavioural and social processes
that complement the domains of biomedicine. However, the field has yet to tap into the full …

Participant perspectives in an HIV cure-related trial conducted exclusively in women in the United States: results from AIDS clinical trials group 5366

K Dubé, L Hosey, K Starr, L Barr, D Evans… - AIDS research and …, 2020 - liebertpub.com
Women remain underrepresented in HIV research. The AIDS Clinical Trials Group (ACTG)
5366 study was the first HIV cure-related trial conducted exclusively in women. Our …

[HTML][HTML] Willingness to participate and take risks in HIV cure research: survey results from 400 people living with HIV in the US

K Dubé, D Evans, L Sylla, J Taylor, BJ Weiner… - Journal of Virus …, 2017 - Elsevier
Introduction Participation in early-phase HIV cure studies includes clinical risks with little to
no likelihood of clinical benefit. Examining the willingness of people living with HIV to …

[HTML][HTML] Multi-stakeholder consensus on a target product profile for an HIV cure

SR Lewin, T Attoye, C Bansbach, B Doehle, K Dubé… - The Lancet …, 2021 - thelancet.com
Developing a cure for HIV is a global priority. Target product profiles are a tool commonly used
throughout the drug development process to align interested parties around a clear set of …

Recommendations for analytical antiretroviral treatment interruptions in HIV research trials—report of a consensus meeting

…, M Caskey, DJ Colby, L Dawson, KL Dong, K Dubé… - The lancet HIV, 2019 - thelancet.com
Analytical antiretroviral treatment interruption (ATI) is an important feature of HIV research,
seeking to achieve sustained viral suppression in the absence of antiretroviral therapy (ART) …

[HTML][HTML] 'Well, it's the risk of the unknown… right?': a qualitative study of perceived risks and benefits of HIV cure research in the United States

K Dubé, J Taylor, L Sylla, D Evans, L Dee, A Burton… - PloS one, 2017 - journals.plos.org
Introduction Biomedical research towards an HIV cure is advancing in the United States and
elsewhere, yet little is known about perceptions of risks and benefits among potential study …

Towards multidisciplinary HIV-cure research: integrating social science with biomedical research

…, AL Ross, JD Auerbach, J Ananworanich, K Dubé… - Trends in …, 2016 - cell.com
The quest for a cure for HIV remains a timely and key challenge for the HIV research community.
Despite significant scientific advances, current HIV therapy regimens do not completely …

How does the timing of antiretroviral therapy initiation in acute infection affect HIV reservoirs?

J Ananworanich, K Dubé… - Current Opinion in HIV and …, 2015 - journals.lww.com
It is clear that early ART has a greater impact in limiting the HIV reservoirs than later treatment.
However, latently infected long-lived memory CD4+ T cells persist in most early treated …

“We need to deploy them very thoughtfully and carefully”: Perceptions of analytical treatment interruptions in HIV cure research in the United States—A qualitative …

K Dubé, D Evans, L Dee, L Sylla, J Taylor… - AIDS Research and …, 2018 - liebertpub.com
Strategies to control HIV in the absence of antiretroviral therapy are needed to cure HIV.
However, such strategies will require analytical treatment interruptions (ATIs) to determine their …

[HTML][HTML] Interrupting antiretroviral treatment in HIV cure research: scientific and ethical considerations

SA Garner, S Rennie, J Ananworanich, K Dube… - Journal of Virus …, 2017 - Elsevier
Over the past several years there has been intense activity directed at the possibility of
achieving remission or eradication of HIV infection. Current assays for the measurement of latent …