Morphologic and biochemical hallmarks of apoptosis

A Saraste, K Pulkki - Cardiovascular research, 2000 - academic.oup.com
Apoptosis is characterised by a series of typical morphological features, such as shrinkage
of the cell, fragmentation into membrane-bound apoptotic bodies and rapid phagocytosis by …

Apoptosis in human acute myocardial infarction

A Saraste, K Pulkki, M Kallajoki, K Henriksen… - Circulation, 1997 - Am Heart Assoc
Background After reopening of the infarct-related coronary artery, cardiomyocytes continue
to die during reperfusion. The mechanisms of cell death have been subject to debate. We …

Fasting is not routinely required for determination of a lipid profile: clinical and laboratory implications including flagging at desirable concentration cut-points—a joint …

…, A von Eckardstein, PR Kamstrup, K Pulkki… - European heart …, 2016 - academic.oup.com
Aims To critically evaluate the clinical implications of the use of non-fasting rather than
fasting lipid profiles and to provide guidance for the laboratory reporting of abnormal non-fasting …

Acute doxorubicin cardiotoxicity involves cardiomyocyte apoptosis

…, K Pulkki, M Kallajoki, M Parvinen, LM Voipio-Pulkki - Cancer research, 2000 - AACR
Despite well-documented cardiotoxic effects, doxorubicin remains a major anticancer agent.
To study the role of myocardial apoptosis following doxorubicin administration, male Wistar …

[HTML][HTML] Effects of n-6 PUFAs compared with SFAs on liver fat, lipoproteins, and inflammation in abdominal obesity: a randomized controlled trial

…, L Johansson, L Persson, J Berglund, K Pulkki… - The American journal of …, 2012 - Elsevier
Background: Replacing SFAs with vegetable PUFAs has cardiometabolic benefits, but the
effects on liver fat are unknown. Increased dietary n-6 PUFAs have, however, also been …

Cardiomyocyte apoptosis and ventricular remodeling after myocardial infarction in rats

…, A Saraste, A Eriksson, K Pulkki… - American Journal …, 2001 - journals.physiology.org
We investigated the role of cardiomyocyte apoptosis in the remodeling of the left ventricle from
24 h to 12 wk after myocardial infarction in the rat. Infarct size planimetry, quantification of …

Prognostic value of cystatin C in acute heart failure in relation to other markers of renal function and NT-proBNP

…, J Melin, K Peuhkurinen, K Pulkki… - European Heart …, 2007 - academic.oup.com
Aims Cystatin C, a novel marker of renal function, has been implicated as a prognostic
marker in cardiovascular disease. We investigated the prognostic value of cystatin C in acute …

Circulating pregnancy-associated plasma protein a predicts outcome in patients with acute coronary syndrome but no troponin I elevation

…, K Pettersson, LM Voipio-Pulkki, P Porela, K Pulkki - Circulation, 2003 - Am Heart Assoc
Background— Risk stratification in troponin (cTn)-negative acute coronary syndrome (ACS)
remains a clinical challenge. We investigated the predictive value of circulating pregnancy-…

Troponin I is released in bloodstream of patients with acute myocardial infarction not in free form but as complex

…, ME Severina, K Pulkki, LM Vuopio-Pulkki… - Clinical …, 1997 - academic.oup.com
Fourteen monoclonal antibodies (mAbs) against human cardiac troponin I (cTnI) were
generated by commonly used experimental techniques. All these antibodies, as well as antibody …

Effects of an isocaloric healthy N ordic diet on insulin sensitivity, lipid profile and inflammation markers in metabolic syndrome–a randomized study (SYSDIET)

…, D Iggman, J Paananen, KJ Pulkki… - Journal of internal …, 2013 - Wiley Online Library
Background Different healthy food patterns may modify cardiometabolic risk. We investigated
the effects of an isocaloric healthy N ordic diet on insulin sensitivity, lipid profile, blood …