Patient management in oncology increasingly relies on imaging for diagnosis, response
assessment, and follow-up. The clinical availability of combined functional/anatomical imaging …

Docosahexaenoic acid (DHA; 22:6n-3) is a critical constituent of the brain, but its metabolism
has not been measured in the human brain in vivo. In monkeys, using positron emission …

Purpose To characterize uptake of 1-amino-3-fluorine 18-fluorocyclobutane-1-carboxylic
acid ( 18 F FACBC) in patients with localized prostate cancer, benign prostatic hyperplasia (…

This work characterizes the uptake of 11 C-acetate in prostate cancer (PCa), benign prostate
hyperplasia, and normal prostate tissue in comparison with multiparametric MRI, whole-…

We evaluated the kinetics of 18 F-sodium fluoride (NaF) and reassessed the recommended
dose, optimal uptake period, and reproducibility using a current-generation PET/CT scanner. …

This prospective pilot study evaluated the ability of Na 18 F PET/CT to detect and monitor
bone metastases over time and its correlation with clinical outcomes and survival in advanced …

BACKGROUND Fluorine 18 fluorodeoxyglucose (FDG) uptake in the myocardium has been
well validated as an indicator of myocardial viability. 1-3 In addition, rubidium-82 and …

Multidrug resistance (MDR) associated with increased expression and function of the P-glycoprotein
(Pgp) efflux pump often causes chemotherapeutic failure in cancer. To provide …

Modern radiation therapy is delivered with great precision, in part by relying on high-resolution
multidimensional anatomic imaging to define targets in space and time. The development …

Background Carbonic anhydrase IX (CA-IX) is a potential imaging biomarker of clear cell
renal cell carcinoma (ccRCC). Here, we report the results of a phase II clinical trial of a small …