User profiles for KYUNG-HAN LEE

Kyung-Han Lee

Professor of Nuclear Medicine, Samsung medical center
Verified email at samsung.com
Cited by 12192

Akt activation preserves cardiac function and prevents injury after transient cardiac ischemia in vivo

T Matsui, J Tao, F del Monte, KH Lee, L Li, M Picard… - Circulation, 2001 - Am Heart Assoc
Background The serine-threonine kinase Akt is activated by several ligand-receptor systems
previously shown to be cardioprotective. Akt activation reduces cardiomyocyte apoptosis in …

[HTML][HTML] Akt participation in the Wnt signaling pathway through Dishevelled

…, K Maemura, MD Layne, SF Yet, KH Lee… - Journal of Biological …, 2001 - ASBMB
Inactivation of glycogen synthase kinase 3β (GSK3β) and the resulting stabilization of free β-catenin
are critical steps in the activation of Wnt target genes. While Akt regulates GSK3α/β …

Focal thyroid lesions incidentally identified by integrated 18F-FDG PET/CT: clinical significance and improved characterization

JY Choi, KS Lee, HJ Kim, YM Shim… - Journal of Nuclear …, 2006 - Soc Nuclear Med
In this retrospective study, we investigated whether the 18 F-FDG uptake pattern and CT
findings improved the accuracy over the standardized uptake value (SUV) for differentiating …

[PDF][PDF] Improved detection of individual nodal involvement in squamous cell carcinoma of the esophagus by FDG PET

JY Choi, KH Lee, YM Shim, KS Lee… - Journal of Nuclear …, 2000 - Soc Nuclear Med
8Common hepaticnodesAlong courseof commonhepatic artery20Celiac nodesAt baseof celiac
arteryPAPara-aortic nodesAlong courseof abdominalaortadistalto celiac trunk* M@ Jified …

Modulation of ventricular function through gene transfer in vivo

…, T Matsui, JL Guerrero, KH Lee… - Proceedings of the …, 1998 - National Acad Sciences
We used a catheter-based technique to achieve generalized cardiac gene transfer in vivo
and to alter cardiac function by overexpressing phospholamban (PL) which regulates the …

Curcumin and Dehydrozingerone Derivatives:  Synthesis, Radiolabeling, and Evaluation for β-Amyloid Plaque Imaging

EK Ryu, YS Choe, KH Lee, Y Choi… - Journal of medicinal …, 2006 - ACS Publications
Alzheimer's disease (AD) is pathologically characterized by the accumulation of amyloid
plaques and neurofibrillary tangles in the brain, and thus, the in vivo imaging of plaques and …

Prognostic Value of Metabolic Tumor Volume Measured by 18F-Fluorodeoxyglucose Positron Emission Tomography in Patients with Esophageal Carcinoma

…, K Kim, SJ Lee, YS Cho, JY Lee, KH Lee… - Annals of Surgical …, 2010 - Springer
Purpose The aim of this study was to evaluate the prognostic value of metabolic tumor
volume (MTV) measured by 18 F-fluorodeoxyglucose positron emission tomography ( 18 F-FDG …

Stereotactic brain injection of human umbilical cord blood mesenchymal stem cells in patients with Alzheimer's disease dementia: a phase 1 clinical trial

…, JM Lee, ST Kim, YS Choe, KH Lee… - … Research & Clinical …, 2015 - Wiley Online Library
Introduction We conducted a phase 1 clinical trial in nine patients with mild‐to‐moderate
Alzheimer's disease to evaluate the safety and dose‐limiting toxicity of stereotactic brain …

Pathogenesis of cerebral microbleeds: in vivo imaging of amyloid and subcortical ischemic small vessel disease in 226 individuals with cognitive impairment

…, ST Kim, KC Kwak, U Yoon, JM Lee, JW Lee… - Annals of …, 2013 - Wiley Online Library
Objective Cerebral microbleeds (CMBs) are a neuroimaging marker of small vessel disease
(SVD) with relevance for understanding disease mechanisms in cerebrovascular disease, …

Prognostic value of 18F‐FDG PET/CT in patients with squamous cell carcinoma of the tonsil: Comparisons of volume‐based metabolic parameters

SH Moon, JY Choi, HJ Lee, YI Son, CH Baek… - Head & …, 2013 - Wiley Online Library
Background The prognostic significance of volume‐based metabolic parameters measured
by 18 F‐fluorodeoxyglucose positron emission tomography/CT ( 18 F‐FDG PET/CT) is not …