Climate change impacts on wind power generation
… where A is the scale parameter and k is the shape parameter. These wind speeds have an
exponential tail, leading to the accumulated probability of extreme wind speeds conforming to …
exponential tail, leading to the accumulated probability of extreme wind speeds conforming to …
[HTML][HTML] DNA damage response in plants: conserved and variable response compared to animals
KO Yoshiyama, K Sakaguchi, S Kimura - Biology, 2013 - mdpi.com
The genome of an organism is under constant attack from endogenous and exogenous
DNA damaging factors, such as reactive radicals, radiation, and genotoxins. Therefore, DNA …
DNA damaging factors, such as reactive radicals, radiation, and genotoxins. Therefore, DNA …
DNA repair in plants
S Kimura, K Sakaguchi - Chemical reviews, 2006 - ACS Publications
… in 2001 under the supervision of Professor Kengo Sakaguchi. He was a research associate
at Tokyo University of Science from 2001 to 2005. He has received a long-term research …
at Tokyo University of Science from 2001 to 2005. He has received a long-term research …
Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
… The gene mutated in AT, ATM (ataxia telangiectasia–mutated), encodes a 370-kD protein
that is a member of a family of proteins related to phosphatidylinositol 3-kinase (PI-3-K) that …
that is a member of a family of proteins related to phosphatidylinositol 3-kinase (PI-3-K) that …
Parameterization improvements and functional and structural advances in version 4 of the Community Land Model
The Community Land Model is the land component of the Community Climate System Model.
Here, we describe a broad set of model improvements and additions that have been …
Here, we describe a broad set of model improvements and additions that have been …
DNA damage activates p53 through a phosphorylation–acetylation cascade
K Sakaguchi, JE Herrera, S Saito, T Miki… - Genes & …, 1998 - genesdev.cshlp.org
Activation of p53-mediated transcription is a critical cellular response to DNA damage. p53
stability and site-specific DNA-binding activity and, therefore, transcriptional activity, are …
stability and site-specific DNA-binding activity and, therefore, transcriptional activity, are …
Characterization of peptides bound to the class I MHC molecule HLA-A2. 1 by mass spectrometry
Antigens recognized by T cells are expressed as peptides bound to major histocompatibility
complex (MHC) molecules. Microcapillary high-performance liquid chromatography-…
complex (MHC) molecules. Microcapillary high-performance liquid chromatography-…
Identification of a human melanoma antigen recognized by tumor-infiltrating lymphocytes associated with in vivo tumor rejection.
…, PF Robbins, K Sakaguchi… - Proceedings of the …, 1994 - National Acad Sciences
The cultured T-cell line TIL1200, established from the tumor-infiltrating lymphocytes (TILs) of
a patient with advanced metastatic melanoma, recognized an antigen on most HLA-A2+ …
a patient with advanced metastatic melanoma, recognized an antigen on most HLA-A2+ …
DNA damage induces phosphorylation of the amino terminus of p53
…, CE Canman, Y Taya, K Sakaguchi… - Genes & …, 1997 - genesdev.cshlp.org
Data are presented demonstrating that DNA damage leads to specific post-translational
modifications of p53 protein. Using two-dimensional peptide mapping of in vivo radiolabeled …
modifications of p53 protein. Using two-dimensional peptide mapping of in vivo radiolabeled …
Identification of the immunodominant peptides of the MART-1 human melanoma antigen recognized by the majority of HLA-A2-restricted tumor infiltrating lymphocytes.
Y Kawakami, S Eliyahu, K Sakaguchi… - The Journal of …, 1994 - rupress.org
Four melanoma proteins, MART-1, gp100, tyrosinase, and tyrosinase-related protein-1 (gp75)
were evaluated for recognition by HLA-A2-restricted melanoma-specific cytotoxic T …
were evaluated for recognition by HLA-A2-restricted melanoma-specific cytotoxic T …