User profiles for K. S. R. Sastry

Konduru Seetharama Sastry

Staff Scientist, Sidra Medicine
Verified email at sidra.org
Cited by 2424

Breast cancer in Arab populations: molecular characteristics and disease management implications

L Chouchane, H Boussen, KSR Sastry - The lancet oncology, 2013 - thelancet.com
Breast cancer is a major health problem in both developing and developed countries. It is the
most frequently diagnosed female malignant disease in Arab populations. The incidence of …

Biological effects of the Auger emitter iodine‐125: A review. Report No. 1 of AAPM Nuclear Medicine Task Group No. 6

KSR Sastry - Medical physics, 1992 - Wiley Online Library
… Rao, VR Narra, RW Howell, VK, Lanka, and KSR Sastry, “Induction of spermhead abnormalities
by incorporated radionuclides: Dependence on subcellular distribution, type of radiation, …

PDGF, TGF-β, and FGF signaling is important for differentiation and growth of mesenchymal stem cells (MSCs): transcriptional profiling can identify markers and …

F Ng, S Boucher, S Koh, KSR Sastry… - Blood, The Journal …, 2008 - ashpublications.org
We compared the transcriptomes of marrow-derived mesenchymal stem cells (MSCs) with
differentiated adipocytes, osteocytes, and chondrocytes derived from these MSCs. Using …

[HTML][HTML] Epinephrine protects cancer cells from apoptosis via activation of cAMP-dependent protein kinase and BAD phosphorylation

KSR Sastry, Y Karpova, S Prokopovich, AJ Smith… - Journal of Biological …, 2007 - ASBMB
The stress hormone epinephrine is known to elicit multiple systemic effects that include
changes in cardiovascular parameters and immune responses. However, information about its …

Radiotoxicity of 125I in Mammalian Cells

…, F Fayad, BM Kinsey, KSR Sastry… - Radiation …, 1987 - meridian.allenpress.com
The radiotoxicity of 125 I in Chinese hamster V79 lung fibroblasts has been studied following
extracellular (Na 125 I), cytoplasmic [ 125 I]iododihydrorhodamine ( 125 I-DR), and nuclear …

Kinetics of Uptake, Retention, and Radiotoxicity of 125IUdR in Mammalian Cells: Implications of Localized Energy Deposition by Auger Processes

AI Kassis, KSR Sastry, SJ Adelstein - Radiation research, 1987 - meridian.allenpress.com
The kinetics of uptake, retention, and radiotoxicity of 125 IUdR have been studied in
proliferating mammalian cells in culture. The radioactivity incorporated into the DNA is directly …

Host ethnicity and virus genotype shape the hepatitis B virus-specific T-cell repertoire

…, C Boni, A Chia, AJ Gehring, KSR Sastry… - Journal of …, 2008 - Am Soc Microbiol
Repertoire composition, quantity, and qualitative functional ability are the parameters that
define virus-specific T-cell responses and are linked with their potential to control infection. We …

Macroscopic dosimetry for radioimmunotherapy: nonuniform activity distributions in solid tumors

RW Howell, DV Rao, KSR Sastry - Medical physics, 1989 - Wiley Online Library
KSR Sastry and DV Rao, “Dosimetry of low energy electrons," in Physics of Nuclear
Medicine: Recent Advances, edited by DV Rao, R. Chandra, and MC Graham, Medical Physics …

Lethality of Auger electrons from the decay of bromine-77 in the DNA of mammalian cells

…, SJ Adelstein, C Haydock, KSR Sastry… - Radiation …, 1982 - meridian.allenpress.com
The uptake and radiotoxicity of bromine-77-deoxyuridine have been studied in V79 cells.
Incorporation of ${}^{77}{\rm BrUdR}$ into DNA of dividing cells is dependent on its …

The question of relative biological effectiveness and quality factor for Auger emitters incorporated into proliferating mammalian cells

…, DV Rao, DY Hou, VR Narra, KSR Sastry - Radiation …, 1991 - meridian.allenpress.com
Sastry and Rao (1) have given a detailed electron spectrum for 125I including conversion …
HOWELL, and KSR SASTRY, In vivo effects of 5.3 MeV alpha particles from Po-210 in …