Targeting of lectinlike oxidized low-density lipoprotein receptor 1 (LOX-1) with 99mTc-labeled anti–LOX-1 antibody: potential agent for imaging of vulnerable plaque

…, N Kume, M Ogawa, N Takai, J Kamihashi… - Journal of Nuclear …, 2008 - Soc Nuclear Med
Lectinlike oxidized low-density lipoprotein (LDL) receptor 1 (LOX-1), a cell surface receptor
for oxidized LDL, has been implicated in vascular cell dysfunction related to plaque instability…

Imaging with radiolabelled anti-membrane type 1 matrix metalloproteinase (MT1-MMP) antibody: potentials for characterizing atherosclerotic plaques

…, Y Zhao, K Nishigori, S Ishino, J Kamihashi… - European journal of …, 2010 - Springer
Purpose Membrane type 1 matrix metalloproteinase (MT1-MMP) activates pro-MMP-2 and
pro-MMP-13 to their active forms and plays important roles in the destabilization of …

Development of a radiolabeled probe for detecting membrane type-1 matrix metalloproteinase on malignant tumors

T Temma, K Sano, Y Kuge, J Kamihashi… - Biological and …, 2009 - jstage.jst.go.jp
MATERIALS AND METHODS Preparation of 99mTc-Anti-MT1-MMP mAb All chemicals
used in this study were commercial products of the highest purity. 99mTc-pertechnetate was …

PET O-15 cerebral blood flow and metabolism after acute stroke in spontaneously hypertensive rats

T Temma, Y Kuge, K Sano, J Kamihashi, N Obokata… - Brain research, 2008 - Elsevier
Hypertension is a major stroke risk factor and is correlated with worse outcome after stroke.
Thus, the effects of hypertension on cerebral hemodynamics and metabolism within an hour …

Radioimmunodetection of membrane type-1 matrix metalloproteinase relevant to tumor malignancy with a pre-targeting method

…, T Temma, Y Kuge, T Kudo, J Kamihashi… - Biological and …, 2010 - jstage.jst.go.jp
Since membrane type-1 matrix metalloproteinase (MT1-MMP) is exclusively expressed in
tumors and is closely associated with metastasis and invasion, MT1-MMP is a potential target …

Achievement of MT1-MMP imaging shortly after radioligand administration by pretargeting strategy with SPECT

T Temma, K Sano, Y Kuge, T Kudo, J Kamihashi, H Saji - 2009 - Soc Nuclear Med
1644 Objectives Membrane type-1 matrix metalloproteinase (MT1-MMP) expressed in tumors
is a potential target for evaluating the malignancy due to its critical role in metastasis and …

Pre-targeting method improves MT1-MMP imaging for evaluating tumor malignancy

K Sano, T Temma, Y Kuge, J Kamihashi, T Kudo, H Saji - 2008 - Soc Nuclear Med
561 Objectives: Since membrane type-1 matrix metalloproteinase (MT1-MMP) is exclusively
expressed in tumors and closely related to metastasis and invasion, MT1-MMP should be a …

An accurate FET model for microwave nonlinear circuit simulation

…, S WATANABE, S KAMIHASHI - IEICE transactions on …, 1995 - search.ieice.org
We propose an accurate FET model for microwave nonlinear circuit simulation, which has
been modified from the Statz model. We have greatly enhanced the accuracy of both dc and …

[HTML][HTML] Use of a Caco-2 permeability assay to evaluate the effects of several Kampo medicines on the drug transporter P-glycoprotein

T Matsumoto, N Kaifuchi, Y Mizuhara, E Warabi… - Journal of natural …, 2018 - Springer
In modern medical care in which Kampo and Western drugs are often combined, it is extremely
important to clarify drug–drug interaction (DDI) to ensure safety and efficacy. However, …

[HTML][HTML] Basic study of drug-drug interaction between memantine and the traditional Japanese Kampo medicine yokukansan

T Matsumoto, K Sekiguchi, Z Kawakami, J Watanabe… - Molecules, 2018 - mdpi.com
Several basic pharmacokinetic and pharmacological studies were conducted as part of a
group of studies to clarify the drug-drug interaction (DDI) between memantine (MEM), a drug …