User profiles for Jundong Zhou

Jundong Zhou

Tsinghua University
Verified email at mails.tsinghua.edu.cn
Cited by 12

Downregulation of miR-132 by promoter methylation contributes to pancreatic cancer development

…, J Hao, F Xie, X Hu, C Liu, J Tong, J Zhou… - …, 2011 - academic.oup.com
MicroRNAs (miRNAs), which regulate gene expression by partial complementarity to the 3′
untranslated region of their target genes, have been implicated in cancer initiation and …

Peptide blocking of PD-1/PD-L1 interaction for cancer immunotherapy

C Li, N Zhang, J Zhou, C Ding, Y Jin, X Cui, K Pu… - Cancer immunology …, 2018 - AACR
Immunotherapy has become a promising alternative therapeutic approach for cancer patients.
Interruption of immune checkpoints, such as CTLA-4 and PD-1, has been verified to be a …

MiRNA-30a-mediated autophagy inhibition sensitizes renal cell carcinoma cells to sorafenib

…, D Gu, X Pan, L Qian, B Xue, D Yang, J Zhou… - Biochemical and …, 2015 - Elsevier
Chemotherapy-induced autophagy activation often contributes to cancer resistance. MiRNA-30a
(miR-30a) is a potent inhibitor of autophagy by downregulating Beclin-1. In this study, …

Tumor cell membrane-based peptide delivery system targeting the tumor microenvironment for cancer immunotherapy and diagnosis

X Meng, J Wang, J Zhou, Q Tian, B Qie, G Zhou… - Acta biomaterialia, 2021 - Elsevier
The development of an effective delivery system for peptides targeting the tumor microenvironment
has always been a hot topic of research in the field of cancer diagnosis and therapy. …

[HTML][HTML] Activation of peroxisome proliferator-activated receptor α (PPARα) suppresses hypoxia-inducible factor-1α (HIF-1α) signaling in cancer cells

J Zhou, S Zhang, J Xue, J Avery, J Wu, SE Lind… - Journal of Biological …, 2012 - ASBMB
Activation of peroxisome proliferator-activated receptor α (PPARα) has been demonstrated to
inhibit tumor growth and angiogenesis, yet the mechanisms behind these actions remain to …

[HTML][HTML] MiR-592 promotes gastric cancer proliferation, migration, and invasion through the PI3K/AKT and MAPK/ERK signaling pathways by targeting Spry2

Y He, Y Ge, M Jiang, J Zhou, D Luo, H Fan… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Gastric cancer (GC) is one of the most prevalent digestive malignancies.
MicroRNAs (miRNAs) are involved in multiple cellular processes, including oncogenesis, …

Box-Level Active Detection

M Lyu, J Zhou, H Chen, Y Huang… - Proceedings of the …, 2023 - openaccess.thecvf.com
Active learning selects informative samples for annotation within budget, which has proven
efficient recently on object detection. However, the widely used active detection benchmarks …

[HTML][HTML] The Nrf2/GCH1/BH4 axis ameliorates radiation-induced skin injury by modulating the ROS cascade

…, Q Zhang, H Yang, H Cao, W Wang, J Zhou… - Journal of Investigative …, 2017 - Elsevier
Radiation-induced skin injury is a common side effect of radiotherapy and can limit the
duration and dose of radiotherapy. Most early work focused on elimination of reactive oxygen …

[HTML][HTML] miR-34a inhibits the migration and invasion of esophageal squamous cell carcinoma by targeting Yin Yang-1

…, H Cao, W Zhu, Y Jiao, J Wu, J Zhou… - Oncology …, 2015 - spandidos-publications.com
Esophageal squamous cell carcinoma (ESCC), one of the most common gastrointestinal
tumors, is known for its high mortality rate. microRNAs (miRNAs) have been reported to play …

Protein and miRNA profiling of radiation-induced skin injury in rats: the protective role of peroxiredoxin-6 against ionizing radiation

…, J Xue, H Cao, Y Tang, X Xu, J Cao, J Zhou… - Free Radical Biology …, 2014 - Elsevier
Radiation-induced skin injury is a serious concern during radiotherapy. However, the molecular
mechanism underlying the pathogenesis of radiation-induced skin injury has not been …