A new family of heparin-binding growth/differentiation factors: increased midkine expression in Wilms' tumor and other human carcinomas
J Tsutsui, K Kadomatsu, S Matsubara, A Nakagawara… - Cancer research, 1993 - AACR
Midkine (MK) and heparin-binding growth-associated molecule/pleiotrophin form a new
family of heparin-binding growth/differentiation factors. We studied MK gene expression in …
family of heparin-binding growth/differentiation factors. We studied MK gene expression in …
Increased midkine gene expression in human gastrointestinal cancers
K Aridome, J Tsutsui, S Takao… - Japanese Journal of …, 1995 - Wiley Online Library
Midkine (MK) is a product of a retinoic acid‐responsive gene, and is a novel growth
differentiation factor. We examined the expression of the MK gene in specimens of 47 surgically …
differentiation factor. We examined the expression of the MK gene in specimens of 47 surgically …
Rho-associated protein kinase inhibitor, Y-27632, induces alterations in adhesion, contraction and motility in cultured human trabecular meshwork cells
T Koga, T Koga, M Awai, J Tsutsui, BYJT Yue… - Experimental eye …, 2006 - Elsevier
We investigated the roles of Rho-associated protein kinase (ROCK) in regulating activities
such as adhesion, contraction and migration in cultured human trabecular meshwork (TM) …
such as adhesion, contraction and migration in cultured human trabecular meshwork (TM) …
A new family of heparin-binding factors: strong conservation of midkine (MK) sequences between the human and the mouse
J Tsutsui, K Uehara, K Kadomatsu, S Matsubara… - Biochemical and …, 1991 - Elsevier
A retinoic acid responsive gene, MK, specifies for a heparin binding factor termed midkine (MK),
which is the initial member of a new protein family involved in regulation of growth and …
which is the initial member of a new protein family involved in regulation of growth and …
Identification of nucleolin as a binding protein for midkine (MK) and heparin-binding growth associated molecule (HB-GAM)
M Take, J Tsutsui, H Obama, M Ozawa… - The Journal of …, 1994 - academic.oup.com
Midkine (MK) is a heparin-binding growth/differentiation factor with a molecular weight of 13
kDa, and is structurally unrelated to fibroblast growth factors (FGF). We studied MK-binding …
kDa, and is structurally unrelated to fibroblast growth factors (FGF). We studied MK-binding …
Midkine is present in the early stage of cerebral infarct
Y Yoshida, M Goto, J Tsutsui, M Ozawa, E Sato… - Developmental brain …, 1995 - Elsevier
Expression of midkine (MK), a growth factor with neurotrophic activities, was examined
immunohistochemically in experimental cerebral infarct of rats. From postoperative day 1 to day 7 …
immunohistochemically in experimental cerebral infarct of rats. From postoperative day 1 to day 7 …
Genomic structure of human midkine (MK), a retinoic acid-responsive growth/differentiation factor
…, S Matsubara, K Kadomatsu, J Tsutsui… - The Journal of …, 1992 - jstage.jst.go.jp
… Tsutsui, and T akashi Muramatsu … in Tsutsui … Tsutsui, J., Uehara, K., Kadomatsu, K.,
Matsubara, S., & Muramatsu, T. (1991) Biochem. Biophys. …
Matsubara, S., & Muramatsu, T. (1991) Biochem. Biophys. …
Simulated tropical cyclones using the National Center for Atmospheric Research community climate model
J Tsutsui, A Kasahara - Journal of Geophysical Research …, 1996 - Wiley Online Library
The possibility of simulating tropical cyclones (TCs) using the National Center for Atmospheric
Research community climate model (CCM2) is explored. Daily outputs from two long‐term …
Research community climate model (CCM2) is explored. Daily outputs from two long‐term …
Midkine as a novel target gene for the Wilms' tumor suppressor gene (WT1).
Y Adachi, S Matsubara, C Pedraza, M Ozawa, J Tsutsui… - Oncogene, 1996 - europepmc.org
Midkine (MK) is a heparin-binding growth factor which is strongly expressed during the
midgestation period of mouse embryogenesis. Wilms' tumor is an embryonal kidney malignancy …
midgestation period of mouse embryogenesis. Wilms' tumor is an embryonal kidney malignancy …
Intraventricular administration of the neurotrophic factor midkine ameliorates hippocampal delayed neuronal death following transient forebrain ischemia in gerbils
Y Yoshida, S Ikematsu, T Moritoyo, M Goto, J Tsutsui… - Brain research, 2001 - Elsevier
Midkine (MK) is a growth factor with neurotrophic activities, and is expressed during the
early stages of experimental cerebral infarction in rats in the zone surrounding the infarct. To …
early stages of experimental cerebral infarction in rats in the zone surrounding the infarct. To …