Most clinical trials exploring various combinations of chemo- and immunotherapy rely on
serial biopsy to provide information on immune response. The aim of this study was to assess …

The effects of in vivo gene transfer of endothelial nitric oxide synthase (eNOS) and inducible
NOS (iNOS) genes on severe atherosclerosis were investigated in rabbits. The recombinant …

The germinal matrix of human brain gives rise to oligodendrocytes and astrocytes after mid‐gestation.
Hemorrhage in the germinal matrix of premature infants is associated with …

A wide range of morphological and biochemical changes occur in the central nervous system
with increasing age. L-carnitine, a naturally occurring compound, plays a vital role in fatty …

Hydrocephalus is associated with reduced blood flow in periventricular white matter. To
investigate hypoxic and oxidative damage in the brains of rats with hydrocephalus, kaolin was …

Purpose. [ 18 F]F-AraG is a radiolabeled nucleoside analog that shows relative specificity
for activated T cells. The aim of this study was to investigate the biodistribution of [ 18 F]F-AraG …

Introduction First Nations and other Aboriginal children are disproportionately affected by
cardiometabolic diseases, including type 2 diabetes (T2D). In T2D, the disruption of insulin …

Although endothelial dysfunction deteriorates diabetic angiopathy, the mechanisms are
obscure. We revealed that high glucose augmented eNOS through stimulation of eNOS mRNA …

Background Patterns of response to immunotherapy differ from traditional cytotoxic drugs,
making clinical decisions concerning response evaluation more challenging. Radiological …

Using the C57BL/6→(C57BL/6 x DBA/2)F 1 -hybrid model of acute graft-versus-host disease
(GVHD), we previously showed that treating the donor mice with palifermin provides …