User profiles for Juliane Weiner
 | Juliane WeinerMedical Department III - Endocrinology, Nephrology, Rheumatology, University of Leipzig … Verified email at medizin.uni-leipzig.de Cited by 796 |
Genomic redistribution of GR monomers and dimers mediates transcriptional response to exogenous glucocorticoid in vivo
Glucocorticoids (GCs) are commonly prescribed drugs, but their anti-inflammatory benefits
are mitigated by metabolic side effects. Their transcriptional effects, including tissue-specific …
are mitigated by metabolic side effects. Their transcriptional effects, including tissue-specific …
[HTML][HTML] Functional changes of the gastric bypass microbiota reactivate thermogenic adipose tissue and systemic glucose control via intestinal FXR-TGR5 crosstalk in …
Background Bariatric surgery remains the most effective therapy for adiposity reduction and
remission of type 2 diabetes. Although different bariatric procedures associate with …
remission of type 2 diabetes. Although different bariatric procedures associate with …
[HTML][HTML] Thyroid hormone status defines brown adipose tissue activity and browning of white adipose tissues in mice
The present study aimed to determine the effect of thyroid hormone dysfunction on brown
adipose tissue activity and white adipose tissue browning in mice. Twenty randomized female …
adipose tissue activity and white adipose tissue browning in mice. Twenty randomized female …
Dissociation Between Brown Adipose Tissue 18F-FDG Uptake and Thermogenesis in Uncoupling Protein 1–Deficient Mice
18 F-FDG PET imaging is routinely used to investigate brown adipose tissue (BAT)
thermogenesis, which requires mitochondrial uncoupling protein 1 (UCP1). It remains uncertain, …
thermogenesis, which requires mitochondrial uncoupling protein 1 (UCP1). It remains uncertain, …
Thyroid hormones and browning of adipose tissue
Thyroid hormone (TH) disorders are associated with profound changes in whole body energy
metabolism. A major TH target is thermogenic brown adipose tissue (BAT), which can be …
metabolism. A major TH target is thermogenic brown adipose tissue (BAT), which can be …
Vaspin suppresses cytokine-induced inflammation in 3T3-L1 adipocytes via inhibition of NFκB pathway
K Zieger, J Weiner, K Krause, M Schwarz… - Molecular and cellular …, 2018 - Elsevier
Vaspin expression is increased in white adipose tissue (WAT) of diet-induced obese mice
and rats and is supposed to compensate HFD-induced inflammatory processes and insulin …
and rats and is supposed to compensate HFD-induced inflammatory processes and insulin …
[HTML][HTML] Alternatives for the worse: Molecular insights into adverse effects of bisphenol a and substitutes during human adipocyte differentiation
A Schaffert, L Krieg, J Weiner, R Schlichting… - Environment …, 2021 - Elsevier
Bisphenol A (BPA), which is used in a variety of consumer-related plastic products, was
reported to cause adverse effects, including disruption of adipocyte differentiation, interference …
reported to cause adverse effects, including disruption of adipocyte differentiation, interference …
[HTML][HTML] The repertoire of Adhesion G protein-coupled receptors in adipocytes and their functional relevance
…, Y Popkova, I Kaczmarek, J Weiner… - International journal of …, 2020 - nature.com
Background G protein-coupled receptors (GPCR) are well-characterized regulators of a
plethora of physiological functions among them the modulation of adipogenesis and adipocyte …
plethora of physiological functions among them the modulation of adipogenesis and adipocyte …
Molecular mechanisms of vaspin action–from adipose tissue to skin and bone, from blood vessels to the brain
Visceral adipose tissue-derived serine protease inhibitor (vaspin) or SERPINA12 according
to the serpin nomenclature was identified together with other genes and gene products that …
to the serpin nomenclature was identified together with other genes and gene products that …
A novel thermoregulatory role for PDE 10A in mouse and human adipocytes
Phosphodiesterase type 10A ( PDE 10A) is highly enriched in striatum and is under evaluation
as a drug target for several psychiatric/neurodegenerative diseases. Preclinical studies …
as a drug target for several psychiatric/neurodegenerative diseases. Preclinical studies …