User profiles for Juergen Kopp

Juergen Kopp

Crystallization Platform Heidelberg University Biochemistry Center BZH
Verified email at bzh.uni-heidelberg.de
Cited by 18492

The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling

K Arnold, L Bordoli, J Kopp, T Schwede - Bioinformatics, 2006 - academic.oup.com
Motivation: Homology models of proteins are of great interest for planning and analysing
biological experiments when no experimental three-dimensional structures are available. …

Dosimetry-guided radioactive iodine treatment in patients with metastatic differentiated thyroid cancer: largest safe dose using a risk-adapted approach

R Dorn, J Kopp, H Vogt, P Heidenreich… - Journal of Nuclear …, 2003 - Soc Nuclear Med
This study is a retrospective analysis of 124 differentiated thyroid cancer patients who underwent
dosimetric evaluation using MIRD methodology over a period of 15 y. The objectives of …

Delayed reverse sural flap for staged reconstruction of the foot and lower leg

…, AD Bach, E Polykandriotis, J Kopp… - Plastic and …, 2005 - journals.lww.com
Background: Soft-tissue defects of the foot and lower leg caused by traumatic injury, tumor
ablation, or infection associated with osteomyelitis often require coverage by flaps. One …

[PDF][PDF] Structure and dynamics of the ATP-bound open conformation of Hsp70 chaperones

R Kityk, J Kopp, I Sinning, MP Mayer - Molecular cell, 2012 - cell.com
Central to the chaperone function of Hsp70s is the transition between open and closed
conformations of their polypeptide substrate binding domain (SBD), which is regulated through …

The SWISS‐MODEL Repository of annotated three‐dimensional protein structure homology models

J Kopp, T Schwede - Nucleic acids research, 2004 - academic.oup.com
The SWISS‐MODEL Repository is a database of annotated three‐dimensional comparative
protein structure models generated by the fully automated homology‐modelling pipeline …

Tissue engineering of cultured skin substitutes

RE Horch, J Kopp, U Kneser, J Beier… - Journal of cellular and …, 2005 - Wiley Online Library
Skin replacement has been a challenging task for surgeons ever since the introduction of
skin grafts by Reverdin in 1871. Recently, skin grafting has evolved from the initial autograft …

[PDF][PDF] Molecular mechanism of J-domain-triggered ATP hydrolysis by Hsp70 chaperones

R Kityk, J Kopp, MP Mayer - Molecular cell, 2018 - cell.com
Efficient targeting of Hsp70 chaperones to substrate proteins depends on J-domain cochaperones,
which in synergism with substrates trigger ATP hydrolysis in Hsp70s and concomitant …

9Å structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments

SO Dodonova, P Aderhold, J Kopp, I Ganeva… - Elife, 2017 - elifesciences.org
10.7554/eLife.26691.001 COPI coated vesicles mediate trafficking within the Golgi apparatus
and between the Golgi and the endoplasmic reticulum. Assembly of a COPI coated vesicle …

Assessment of CASP7 predictions for template‐based modeling targets

J Kopp, L Bordoli, JND Battey, F Kiefer… - Proteins: Structure …, 2007 - Wiley Online Library
This manuscript presents the assessment of the template‐based modeling category of the
seventh Critical Assessment of Techniques for Protein Structure Prediction (CASP7). The …

The SWISS-MODEL Repository: new features and functionalities

J Kopp, T Schwede - Nucleic acids research, 2006 - academic.oup.com
The SWISS-MODEL Repository is a database of annotated 3D protein structure models
generated by the SWISS-MODEL homology-modelling pipeline. As of September 2005, the …