Genetic predisposition in anti‐LGI1 and anti‐NMDA receptor encephalitis

…, A Juranek, RD Kanitz, J Obrocki… - Annals of …, 2018 - Wiley Online Library
We performed a genome‐wide association study in 1,194 controls and 150 patients with anti‐N‐methyl‐D‐aspartate
receptor (anti‐NMDAR, n = 96) or anti‐leucine‐rich glioma‐…

A voxel-based PET investigation of the long-term effects of “Ecstasy” consumption on brain serotonin transporters

…, K Petersen, B Nebeling, J Obrocki… - American Journal of …, 2004 - Am Psychiatric Assoc
OBJECTIVE: Recent functional imaging studies have reported evidence of alterations in the
serotonergic system induced by 3,4-methylenedioxymethamphetamine (MDMA), or “Ecstasy.…

[HTML][HTML] Clinical manifestations and immunomodulatory treatment experiences in psychiatric patients with suspected autoimmune encephalitis: a case series of 91 …

…, K Winter, N Zumdick, A Drews, J Obrocki… - Molecular …, 2022 - nature.com
Autoimmune encephalitis (AE) can rarely manifest as a predominantly psychiatric syndrome
without overt neurological symptoms. This study’s aim was to characterize psychiatric …

Long-term effects of “ecstasy” use on serotonin transporters of the brain investigated by PET

…, B Nebeling, K Petersen, J Obrocki… - Journal of Nuclear …, 2003 - Soc Nuclear Med
Alterations of the serotonergic system due to ecstasy consumption have been extensively
documented in recent literature. However, reversibility of these neurotoxic effects still remains …

Ecstasy–long-term effects on the human central nervous system revealed by positron emission tomography

J Obrocki, R Buchert, O Väterlein… - The British Journal of …, 1999 - cambridge.org
BackgroundThe main psychotropic agent of the popular illicit drug ecstasy is 3,4-methylenedioxymethamphetamine
(MDMA). In the light of animal studies and examinations of human …

Effects of behavioral therapy or pharmacotherapy on brain glucose metabolism in subjects with obsessive–compulsive disorder as assessed by brain FDG PET

…, M Rufer, A Weiss, I Hand, M Clausen, J Obrocki - Psychiatry Research …, 2010 - Elsevier
This prospective study investigated the effect of pharmacotherapy (PT) and cognitive
behavioral therapy (CBT) on cerebral glucose metabolism in adults with obsessive–compulsive …

Reversibility of ecstasy-induced reduction in serotonin transporter availability in polydrug ecstasy users

…, R Thomasius, K Petersen, F Wilke, J Obrocki… - European journal of …, 2006 - Springer
Purpose Animal data suggest that the synthetic drug ecstasy may damage brain serotonin
neurons. Previously we reported protracted reductions in the availability of the serotonin …

[PDF][PDF] Anhaltende neurotoxische Schaden durch Ecstasy

J Obrocki, B Andresen, A Schmoldt… - … Mitteilungen-Ausgabe A, 2001 - mikusweb.de
Der Missbrauch der synthetischen Droge Ecstasy ist in westlichen Industriestaaten weit
verbreitet und mittlerweile zu einem gesundheitspolitischen Problem geworden. Neben den von …

Cell surface antibody–associated neurodegeneration: The case of anti-IgLON5 antibodies

RC Dale, S Ramanathan - Neurology, 2017 - AAN Enterprises
Cell surface autoantibodies have become important biomarkers of acquired autoimmune
CNS disorders, and typically define potentially severe but treatable acquired autoimmune …

IgLON5: a case with predominant cerebellar tau deposits and leptomeningeal inflammation

F Schöberl, J Levin, J Remi, N Goldschagg, O Eren… - Neurology, 2018 - AAN Enterprises
In 2014, a novel tauopathy characterized by REM sleep behavior disorder (RBD), sleep apnea,
and stridor was first reported. Association with serum and CSF antibodies against IgLON5…