User profiles for Joshua Grimes

Joshua Grimes

Bayer Inc.
Verified email at bayer.com
Cited by 419

Comparison of internal dose estimates obtained using organ‐level, voxel S value, and Monte Carlo techniques

J Grimes, A Celler - Medical physics, 2014 - Wiley Online Library
Purpose: The authors’ objective was to compare internal dose estimates obtained using the
Organ Level Dose Assessment with Exponential Modeling (OLINDA/EXM) software, the …

Hydrodynamics of pilot-scale bubble columns: effect of internals

AA Youssef, ME Hamed, JT Grimes… - Industrial & …, 2013 - ACS Publications
The gas holdup and bubble characteristics are key parameters that affect the performance
of bubble columns. An experimental study of the effect of heat exchanging internals on the …

improved CT number stability across patient size using dual‐energy CT virtual monoenergetic imaging

G Michalak, J Grimes, J Fletcher, A Halaweish… - Medical …, 2016 - Wiley Online Library
Purpose: The purpose of this study was to evaluate, over a wide range of phantom sizes, CT
number stability achieved using two techniques for generating dual‐energy computed …

Patient-specific radiation dosimetry of 99mTc-HYNIC-Tyr3-octreotide in neuroendocrine tumors

J Grimes, A Celler, B Birkenfeld… - Journal of Nuclear …, 2011 - Soc Nuclear Med
99m Tc-hydrazinonicotinamide-Tyr 3 -octreotide ( 99m Tc-HYNIC-TOC) is increasingly
gaining acceptance as a new radiopharmaceutical for the diagnosis of pathologic lesions …

The accuracy and reproducibility of SPECT target volumes and activities estimated using an iterative adaptive thresholding technique

J Grimes, A Celler, S Shcherbinin… - Nuclear medicine …, 2012 - journals.lww.com
Objective Our aim was to design a practical and reproducible image segmentation method
for calculations of total absorbed doses in organs and tumours for internally delivered …

JADA: a graphical user interface for comprehensive internal dose assessment in nuclear medicine

J Grimes, C Uribe, A Celler - Medical physics, 2013 - Wiley Online Library
Purpose: The main objective of this work was to design a comprehensive dosimetry package
that would keep all aspects of internal dose calculation within the framework of a single …

The influence of focal spot blooming on high‐contrast spatial resolution in CT imaging

J Grimes, X Duan, L Yu, AF Halaweish, N Haag… - Medical …, 2015 - Wiley Online Library
Purpose: The objective of this work was to investigate focal spot blooming effects on the
spatial resolution of CT images and to evaluate an x‐ray tube that uses dynamic focal spot …

Selection of optimal tube potential settings for dual-energy CT virtual mono-energetic imaging of iodine in the abdomen

G Michalak, J Grimes, J Fletcher, A Halaweish, L Yu… - Abdominal …, 2017 - Springer
Purpose To determine the appropriate tube potential settings for dual-source, dual-energy
data acquisition across a range of phantom sizes, and to determine the optimal photon …

Implementation and evaluation of a protocol management system for automated review of CT protocols

J Grimes, S Leng, Y Zhang, T Vrieze… - Journal of applied …, 2016 - Wiley Online Library
Protocol review is important to decrease the risk of patient injury and increase the
consistency of CT image quality. A large volume of CT protocols makes manual review labor‐intensive…

Patient-specific internal dose calculation techniques for clinical use in targeted radionuclide therapy

J Grimes - 2013 - open.library.ubc.ca
The objective of this thesis was to investigate and develop a set of methods for accurate dose
calculation that would be practical to implement into routine clinical use. Towards this aim, …