User profiles for Joseph Ippolito

Joseph E. Ippolito

- Verified email at mir.wustl.edu - Cited by 3610

Joseph A. Ippolito, MD

- Verified email at njms.rutgers.edu - Cited by 770

Prostate cancer, version 2.2019, NCCN clinical practice guidelines in oncology

…, CS Higano, EM Horwitz, M Hurwitz, JE Ippolito… - Journal of the National …, 2019 - jnccn.org
The NCCN Guidelines for Prostate Cancer include recommendations regarding diagnosis,
risk stratification and workup, treatment options for localized disease, and management of …

RNA tertiary interactions in the large ribosomal subunit: the A-minor motif

P Nissen, JA Ippolito, N Ban… - Proceedings of the …, 2001 - National Acad Sciences
Analysis of the 2.4-Å resolution crystal structure of the large ribosomal subunit from Haloarcula
marismortui reveals the existence of an abundant and ubiquitous structural motif that …

[PDF][PDF] The structures of four macrolide antibiotics bound to the large ribosomal subunit

JL Hansen, JA Ippolito, N Ban, P Nissen, PB Moore… - Molecular cell, 2002 - cell.com
Crystal structures of the Haloarcula marismortui large ribosomal subunit complexed with the
16-membered macrolide antibiotics carbomycin A, spiramycin, and tylosin and a 15-…

NCCN guidelines® insights: prostate cancer, version 1.2023: featured updates to the NCCN guidelines

…, X Gao, S Gupta, T Guzzo, JE Ippolito… - Journal of the National …, 2022 - jnccn.org
The NCCN Guidelines for Prostate Cancer address staging and risk assessment after a
prostate cancer diagnosis and include management options for localized, regional, recurrent, …

NCCN guidelines insights: Prostate cancer, version 1.2021: Featured updates to the NCCN guidelines

…, TA Farrington, X Gao, EM Horwitz, JE Ippolito… - Journal of the National …, 2021 - jnccn.org
The NCCN Guidelines for Prostate Cancer address staging and risk assessment after a
prostate cancer diagnosis and include management options for localized, regional, and …

Potent noncovalent inhibitors of the main protease of SARS-CoV-2 from molecular sculpting of the drug perampanel guided by free energy perturbation calculations

…, EA Stone, M Deshmukh, JA Ippolito… - ACS central …, 2021 - ACS Publications
Starting from our previous finding of 14 known drugs as inhibitors of the main protease (M
pro ) of SARS-CoV-2, the virus responsible for COVID-19, we have redesigned the weak hit …

Hydrogen bond stereochemistry in protein structure and function

JA Ippolito, RS Alexander, DW Christianson - Journal of molecular biology, 1990 - Elsevier
Fifty high resolution protein structures from the Brookhaven Protein Data Bank have been
analyzed for recurring motifs in hydrogen bond stereochemistry. Although an exhaustive …

Crystal structure of the oxazolidinone antibiotic linezolid bound to the 50S ribosomal subunit

JA Ippolito, ZF Kanyo, D Wang… - Journal of medicinal …, 2008 - ACS Publications
The oxazolidinone antibacterials target the 50S subunit of prokaryotic ribosomes. To gain
insight into their mechanism of action, the crystal structure of the canonical oxazolidinone, …

Identification of 14 known drugs as inhibitors of the main protease of SARS-CoV-2

…, J Tirado-Rives, M Deshmukh, JA Ippolito… - ACS medicinal …, 2020 - ACS Publications
A consensus virtual screening protocol has been applied to ca. 2000 approved drugs to seek
inhibitors of the main protease (M pro ) of SARS-CoV-2, the virus responsible for COVID-19…

[HTML][HTML] Molecular properties of adult mouse gastric and intestinal epithelial progenitors in their niches

…, DG Leip, M Lovett, SW Clifton, JE Ippolito… - Journal of biological …, 2006 - ASBMB
We have sequenced 36,641 expressed sequence tags from laser capture microdissected
adult mouse gastric and small intestinal epithelial progenitors, obtaining 4031 and 3324 …