The employment of drugs acting on the central nervous system has been predicated largely
on an empirical basis, the anticholinesterase compounds serving as an exception. As our …

… Preliminary reports of this study have been published in abstract form (Trapp and Bernsohn
… 15 days during EFA deficiency (Trapp and Bernsohn, unpublished results). Thus one would …

The localization and properties of soluble and bound esterases of subcellular fractions of rat
brain have been investigated. Bound esterases were extracted with 1% Triton X-100 and …

Neurons, astrocytes, oligodendrocytes, and myelin were prepared from 21‐day‐old rat
brain at various times after intracerebral injection of [1‐ 14 C]linolenate. Comparisons of …

3. By the zvmogram technique at least 18 bands active against naphthol esters can be
separated. Hydrolysis of esters of o’hain length gr (’at (’r than the butyrate is not demonstrable. 4. …

As many as 7 bands of enzymatic activity against choline esters are demonstrable in human,
rat and cat sera by starch gel electrophoresis. The evidence suggests that these bands …

1. Starch gel electrophoresis of rat brain homogenates has demonstrated 9 esterases which
hydrolyze α-naphthyl acetate and naphthol AS-acetate. One of these has been identified as …

Inhibitory properties of 3 chlorpromazine analogues show that oxidation at the sulfur atom,
abolishes inhibition of ATP-ase and cytochrome oxidase systems by chlorpromazine. 2. …

Publisher Summary This chapter discusses multiple molecular forms of brain hydrolases. The
various hydrolases are separated by vertical starch-gel electrophoresis, and visualization …

H ISTOCH Page 1 42 LETTE1t TO THE E1)ITOR Fi;. 5. (left) Front the parenchymal cell of a
rabbit liver after 60 minutes incubation in the ATP me(hum. Activity is prominent in patches of …