Methods We studied 36 cancer patients who underwent chemotherapy, including
doxorubicin, to assess [123I] MIBG and 111In-antimyosin uptake in the course of doxorubicin …

Background 123 I-labeled metaiodobenzylguanidine ( 123 I-MIBG) is used increasingly to
assess cardiac adrenergic neuron function. Few studies have reported data on myocardial …

Background Sarcomas exhibit low expression of factors related to immune response, which
could explain the modest activity of PD-1 inhibitors. A potential strategy to convert a cold into …

Gastrointestinal stromal tumor (GIST) is the most common malignant neoplasm of mesenchymal
origin. GIST spans a wide clinical spectrum that ranges from tumors with essentially no …

Background Solitary fibrous tumour is an ultra-rare sarcoma, which encompasses different
clinicopathological subgroups. The dedifferentiated subgroup shows an aggressive course …

Primary malignant bone tumors are uncommon and heterogeneous malignancies. This
document is a guideline developed by the Spanish Group for Research on Sarcoma with the …

11522 Background: Herein, we present the results of the cohort on advanced bone sarcoma
patients of the phase II part of the IMMUNOSARC study (NCT03277924), a European …

BACKGROUND: In KIT‐expressing Ewing sarcoma cell lines, the addition of doxorubicin to
imatinib increases apoptosis, compared with imatinib or doxorubicin alone. On the basis of …

Patients with localized high-risk soft tissue sarcomas (STS) of the limbs and trunk wall still
have a considerable metastatic recurrence rate of more than 50%, in spite of adjuvant …

Aim Today, free margin surgery is the gold-standard management for soft-tissue sarcoma
patients and one of the most important predictors of recurrence and survival. To obtain optimal …