Systematic reviews and meta-analyses are essential to summarize evidence relating to
efficacy and safety of health care interventions accurately and reliably. The clarity and …

Background In the era of evidence based medicine, with systematic reviews as its cornerstone,
adequate quality assessment tools should be available. There is currently a lack of a …

Importance Cannabis and cannabinoid drugs are widely used to treat disease or alleviate
symptoms, but their efficacy for specific indications is not clear. Objective To conduct a …

Systematic reviews and meta-analyses are a key element of evidence-based healthcare, yet
they remain in some ways mysterious. Why did the authors select certain studies and reject …

Background Throughout history, doctor-patient relationships have been acknowledged as
having an important therapeutic effect, irrespective of any prescribed drug or treatment. We …

Objectives To assess the association between infant size or growth and subsequent obesity
and to determine if any association has been stable over time. Design Systematic review. …

Objective To develop ROBIS, a new tool for assessing the risk of bias in systematic reviews (rather
than in primary studies). Study Design and Setting We used four-stage approach to …

Clinical prediction models combine multiple predictors to estimate risk for the presence of a
particular condition (diagnostic models) or the occurrence of a certain event in the future (…

Background Within systematic reviews, when searching for relevant references, it is
advisable to use multiple databases. However, searching databases is laborious and time-…

OBJECTIVE--To establish whether there is evidence of the efficacy of homoeopathy from
controlled trials in humans. DESIGN--Criteria based meta-analysis. Assessment of the …