To optimize the injected dose of radiopharmaceutical in PET, one needs to know its
relationship to some metric of data quality for individual patient scans, such as noise-equivalent …

Introduction Bone marrow-derived multipotent adult progenitor cells (MAPCs) are adult
allogeneic adherent stem cells currently investigated clinically for use in acute respiratory …

Human infections with highly pathogenic avian influenza A (H5N1) virus are frequently fatal
but the mechanisms of disease remain ill-defined. H5N1 infection is associated with intense …

Pulmonary arterial hypertension (PAH) is increased in HIV, but its pathogenesis is not fully
understood. Nonhuman primates infected with simian immunodeficiency virus (SIV) or SIV-…

The use of x-ray computed tomography (CT)-based attenuation correction for positron emission
tomography (PET) in PET/CT systems requires the transformation of CT Hounsfield units (…

The Regional Biocontainment Laboratory (RBL) at the University of Pittsburgh is a state of
the art ABSL 3 facility that supports research on highly pathogenic viruses and bacteria. …

We measured the whole-body distribution of intravenously injected 11 C-N-propylnorapomorphine
( 11 C-NPA), a dopamine agonist PET tracer, in human subjects and determined the …

Pulmonary arterial hypertension (PAH) is a life-threatening disease with higher incidence in
HIV-infected compared with noninfected patients. SIV-infected NHP develop clinical …

Purpose We measure the whole-body distribution of IV injected [ 11 C]Flumazenil (FMZ) as
a function of time in adult subjects and determine the absorbed radiation doses. Procedures …

Accurate anatomic localization of functional abnormalities seen with PET is known to be
problematic. Even though nonspecific tracers such as 18 F-FDG visualize certain normal …