Early enrichment (EE) programs provide a well-established approach to mitigate the deleterious
effects of childhood adversity. To better understand the therapeutic features of EE, in the …

For decades, the ketogenic diet has been an effective treatment of intractable epilepsy in
children. Childhood epilepsy is pharmacoresistant in 25–40 % of patients taking the current …

50 Hepatic Gap Junction Inhibition Limits Liver Injury and Inflammation in Non-alcoholic
Steatohepatitis (NASH) 51 A lipotoxic m Page 1 50 Hepatic Gap Junction Inhibition Limits Liver …

Purpose: Based on our previous identification of a mutation in a microfibril-associated gene
in a dog model of glaucoma, we formed the hypothesis that glaucoma may be caused by …

Purpose: Sartan drugs are typically prescribed to treat a number of common diseases, such
as hypertension and heart disease. Previous studies have shown the beneficial effect of …

Background: Significant changes in hepatic gene expression are noted in patients with non-alcoholic
fatty liver disease (NAFLD). We aimed to determine if significant changes in gene …

Purpose: Recently we found that mice with microfibril deficiencies due to mutations in the
fibrillin-1 gene (fbn1) have thin central cornea thickness (CCT). We also found that although …

Background and objective The relationship between age and asthma phenotypes is
important as population is ageing, asthma is becoming common in older ages and recently …

Background ANDHI was done to assess the efficacy of benralizumab, including onset of effect
and impact on health-related quality of life (HRQOL), exacerbation rate, lung function, and …

1770 Objectives We Previously identified brain regions with decreased immediate early
gene (IEG) expression in isolation reared (IR) rats ( Levine et al., 2008). In the current study, …