A network of interconnected brain regions, including orbitofrontal, ventral striatal, amygdala,
and midbrain areas, has been widely implicated in a number of aspects of food reward. …

Nutritional state (eg fasted vs. fed) and different food stimuli (eg high‐calorie vs. low‐calorie,
or appetizing vs. bland foods) are both recognized to change activity in brain reward …

[ 11 C]-(+)-PHNO is a D3 preferring PET radioligand which has recently opened the
possibility of imaging D3 receptors in the human brain in vivo. This imaging tool allows …

Obesity is a major public health issue worldwide. Understanding how the brain controls
appetite offers promising inroads toward new therapies for obesity. Peptide YY (PYY) and …

Electrophysiological recording in the anterior superior temporal sulcus (STS) of monkeys
has demonstrated separate cell populations responsive to direct and averted gaze [1, 2]. …

The anterior insula has been implicated in coding disgust from facial, pictorial and olfactory
cues, and in the experience of this emotion. Personality research has shown considerable …

Symptoms of cognitive impairment during smoking withdrawal can be ameliorated by
nicotine replacement. To define brain mechanisms contributing to this therapeutic effect, we …

Gaze direction is an important social signal in humans and other primates. In this study, we
used an adaptation paradigm to investigate the functional organization of gaze perception in …

BACKGROUND: Dopamine D 3 receptors are involved in the pathophysiology of several
neuropsychiatric conditions. [ 11 C]-(+)-PHNO is a radiolabeled D 2 and D 3 agonist, suitable …

[ 11 C]PHNO is a D 2 /D 3 agonist positron emission tomography radiotracer, with higher in
vivo affinity for D 3 than for D 2 receptors. As [ 11 C]-( + )-PHNO is an agonist, its in vivo …