Regional myocardial sympathetic denervation predicts the risk of sudden cardiac arrest in ischemic cardiomyopathy
Objectives : The PAREPET (Prediction of ARrhythmic Events with Positron Emission
Tomography) study sought to test the hypothesis that quantifying inhomogeneity in myocardial …
Tomography) study sought to test the hypothesis that quantifying inhomogeneity in myocardial …
Guidelines for experimental models of myocardial ischemia and infarction
Myocardial infarction is a prevalent major cardiovascular event that arises from myocardial
ischemia with or without reperfusion, and basic and translational research is needed to better …
ischemia with or without reperfusion, and basic and translational research is needed to better …
Risk stratification for sudden cardiac death: a plan for the future
…, R Boineau, AE Buxton, ME Cain, JM Canty Jr… - Circulation, 2014 - Am Heart Assoc
An American Heart Association Scientific Statement addressed the process of risk stratification
and incorporation of novel markers. 6 The Table summarizes the phases of evaluation of …
and incorporation of novel markers. 6 The Table summarizes the phases of evaluation of …
Hibernating myocardium: chronically adapted to ischemia but vulnerable to sudden death
JM Canty Jr, G Suzuki, MD Banas, F Verheyen… - Circulation …, 2004 - Am Heart Assoc
The inability to reproduce spontaneous ventricular fibrillation in an animal model of chronic
coronary artery disease has limited advances in understanding mechanisms of sudden …
coronary artery disease has limited advances in understanding mechanisms of sudden …
Preload induces troponin I degradation independently of myocardial ischemia
…, BJ Schaus, JA Fallavollita, TC Lee, JM Canty Jr - Circulation, 2001 - Am Heart Assoc
Background—Although global ischemia induces troponin I (TnI) degradation, regional ischemia
does not. We hypothesized that this disparity is related to preload-induced proteolysis, …
does not. We hypothesized that this disparity is related to preload-induced proteolysis, …
Phenotypic changes of adult porcine mesenchymal stem cells induced by prolonged passaging in culture
…, E Kong, G Suzuki, K Sato, JM Canty… - Journal of cellular …, 2005 - Wiley Online Library
The in vitro culture of porcine bone marrow‐derived mesenchymal stem cells (MSCs) was
used for the investigation of adult stem cell biology. Isolated porcine MSCs possessed the …
used for the investigation of adult stem cell biology. Isolated porcine MSCs possessed the …
[HTML][HTML] The microRNA regulatory landscape of MSC-derived exosomes: a systems view
Mesenchymal stem cell (MSC)-derived exosomes mediate tissue regeneration in a variety
of diseases including ischemic heart injury, liver fibrosis, and cerebrovascular disease. …
of diseases including ischemic heart injury, liver fibrosis, and cerebrovascular disease. …
Regulation of coronary blood flow in health and ischemic heart disease
DJ Duncker, A Koller, D Merkus, JM Canty Jr - Progress in cardiovascular …, 2015 - Elsevier
The major factors determining myocardial perfusion and oxygen delivery have been
elucidated over the past several decades, and this knowledge has been incorporated into the …
elucidated over the past several decades, and this knowledge has been incorporated into the …
ESC Working Group on Coronary Pathophysiology and Microcirculation position paper on 'coronary microvascular dysfunction in cardiovascular disease'
Although myocardial ischaemia usually manifests as a consequence of atherosclerosis-dependent
obstructive epicardial coronary artery disease, a significant percentage of patients …
obstructive epicardial coronary artery disease, a significant percentage of patients …
[HTML][HTML] TRAK adaptors regulate the recruitment and activation of dynein and kinesin in mitochondrial transport
Mitochondrial transport along microtubules is mediated by Miro1 and TRAK adaptors that
recruit kinesin-1 and dynein-dynactin. To understand how these opposing motors are …
recruit kinesin-1 and dynein-dynactin. To understand how these opposing motors are …