In vivo VEGF imaging with radiolabeled bevacizumab in a human ovarian tumor xenograft
…, GA Hospers, NH Mulder, JR De Jong… - Journal of Nuclear …, 2007 - Soc Nuclear Med
Vascular endothelial growth factor (VEGF), released by tumor cells, is an important growth
factor in tumor angiogenesis. The humanized monoclonal antibody bevacizumab blocks VEGF…
factor in tumor angiogenesis. The humanized monoclonal antibody bevacizumab blocks VEGF…
Development and characterization of clinical-grade 89Zr-trastuzumab for HER2/neu immunoPET imaging
…, J Bart, JR de Jong, EGE de Vries… - Journal of nuclear …, 2009 - Soc Nuclear Med
The anti–human epidermal growth factor receptor 2 (HER2/neu) antibody trastuzumab is
administered to patients with HER2/neu-overexpressing breast cancer. Whole-body …
administered to patients with HER2/neu-overexpressing breast cancer. Whole-body …
89Zr-bevacizumab PET imaging in primary breast cancer
…, JR de Jong, J Bart, J de Vries… - Journal of nuclear …, 2013 - Soc Nuclear Med
Vascular endothelial growth factor (VEGF)-A is overexpressed in most malignant and
premalignant breast lesions. VEGF-A can be visualized noninvasively with PET imaging and using …
premalignant breast lesions. VEGF-A can be visualized noninvasively with PET imaging and using …
[HTML][HTML] Physiological interaction of heart and lung in thoracic irradiation
…, RA De Boer, MG Dickinson, JR De Jong… - International Journal of …, 2012 - Elsevier
INTRODUCTION: The risk of early radiation-induced lung toxicity (RILT) limits the dose and
efficacy of radiation therapy of thoracic tumors. In addition to lung dose, coirradiation of the …
efficacy of radiation therapy of thoracic tumors. In addition to lung dose, coirradiation of the …
6-[F-18]Fluoro-l-Dihydroxyphenylalanine Positron Emission Tomography Is Superior to Conventional Imaging with 123I-Metaiodobenzylguanidine Scintigraphy …
…, MEJ Pijl, IP Kema, JR de Jong… - The Journal of …, 2009 - academic.oup.com
… Johan R. de Jong … For correlations, Spearman’s r test was calculated. A P value was
considered significant in case of values <0.05, two sided. Statistical tests were performed using the …
considered significant in case of values <0.05, two sided. Statistical tests were performed using the …
89Zr-bevacizumab PET visualizes heterogeneous tracer accumulation in tumor lesions of renal cell carcinoma patients and differential effects of antiangiogenic …
…, JR de Jong, IJ de Jong, S de Haas… - Journal of Nuclear …, 2015 - Soc Nuclear Med
No validated predictive biomarkers for antiangiogenic treatment of metastatic renal cell
carcinoma (mRCC) exist. Tumor vascular endothelial growth factor A (VEGF-A) level may be …
carcinoma (mRCC) exist. Tumor vascular endothelial growth factor A (VEGF-A) level may be …
89Zr-bevacizumab PET of early antiangiogenic tumor response to treatment with HSP90 inhibitor NVP-AUY922
…, WF den Dunnen, H Hollema, JR de Jong… - Journal of Nuclear …, 2010 - Soc Nuclear Med
Angiogenesis is a critical step in tumor development, in which vascular endothelial growth
factor (VEGF) is a key growth aspect. Heat shock protein 90 (HSP90), a molecular chaperone, …
factor (VEGF) is a key growth aspect. Heat shock protein 90 (HSP90), a molecular chaperone, …
[HTML][HTML] 89Zr-trastuzumab PET supports clinical decision making in breast cancer patients, when HER2 status cannot be determined by standard work up
…, AH Brouwers, MN Lub-de Hooge, JR de Jong… - European journal of …, 2018 - Springer
89Zr-trastuzumab PET supports clinical decision making in breast cancer patients, when
HER2 status cannot be determined by standard work up | European Journal of Nuclear …
HER2 status cannot be determined by standard work up | European Journal of Nuclear …
VEGF-PET imaging is a noninvasive biomarker showing differential changes in the tumor during sunitinib treatment
…, FJ Warnders, AH Brouwers, JR de Jong… - Cancer research, 2011 - AACR
Non-invasive imaging of angiogenesis could ease the optimization of antiangiogenesis
treatments for cancer. In this study, we evaluated the role of VEGF-PET as a biomarker of …
treatments for cancer. In this study, we evaluated the role of VEGF-PET as a biomarker of …
Repeatability of 18F‐FDG PET radiomic features: A phantom study to explore sensitivity to image reconstruction settings, noise, and delineation method
E Pfaehler, RJ Beukinga, JR de Jong… - Medical …, 2019 - Wiley Online Library
Background 18 F‐fluoro‐2‐deoxy‐D‐Glucose positron emission tomography ( 18 F‐ FDG
PET ) radiomics has the potential to guide the clinical decision making in cancer patients, but …
PET ) radiomics has the potential to guide the clinical decision making in cancer patients, but …