User profiles for Joel Karp

Joel S Karp

University of Pennsylvania
Verified email at pennmedicine.upenn.edu
Cited by 17149

Benefit of time-of-flight in PET: experimental and clinical results

JS Karp, S Surti, ME Daube-Witherspoon… - Journal of Nuclear …, 2008 - Soc Nuclear Med
Significant improvements have made it possible to add the technology of time-of-flight (TOF)
to improve PET, particularly for oncology applications. The goals of this work were to …

Total-body PET: maximizing sensitivity to create new opportunities for clinical research and patient care

SR Cherry, T Jones, JS Karp, J Qi… - Journal of Nuclear …, 2018 - Soc Nuclear Med
PET is widely considered the most sensitive technique available for noninvasively studying
physiology, metabolism, and molecular pathways in the living human being. However, the …

[PDF][PDF] Continuous-slice PENN-PET: a positron tomograph with volume imaging capability

JS Karp, G Muehllehner, DA Mankoff… - Journal of Nuclear …, 1990 - Soc Nuclear Med
Tomograph with Volume Imaging Capability Page 1 formance of this instrument, which is
based on a pre viously constructed single-slice version (1), is described in this paper,…

[HTML][HTML] State of the art in total body PET

S Vandenberghe, P Moskal, JS Karp - EJNMMI physics, 2020 - Springer
The idea of a very sensitive positron emission tomography (PET) system covering a large
portion of the body of a patient already dates back to the early 1990s. In the period 2000–2010, …

Positron emission tomography

G Muehllehner, JS Karp - Physics in Medicine & Biology, 2006 - iopscience.iop.org
The developments in positron emission tomography (PET) are reviewed with an emphasis
on instrumentation for clinical PET imaging. After a brief summary of positron imaging before …

Evidence of myocardial hibernation in the septic heart

…, PD Acton, R Zhou, VA Ferrari, JS Karp… - Critical care …, 2005 - journals.lww.com
Objective: Myocardial hibernation is an adaptive response to ischemia and hypoxia. Hibernating
cardiomyocytes are reversibly hypocontractile and demonstrate characteristic metabolic …

Performance of Philips Gemini TF PET/CT scanner with special consideration for its time-of-flight imaging capabilities

…, AE Perkins, J Kolthammer, JS Karp - Journal of Nuclear …, 2007 - Soc Nuclear Med
Results from a new PET/CT scanner using lutetium-yttrium oxyorthosilicate (LYSO) crystals
for the PET component are presented. This scanner, which operates in a fully 3-dimensional …

Consensus recommendations for the use of 18F-FDG PET as an indicator of therapeutic response in patients in National Cancer Institute Trials

…, S Bacharach, MM Graham, J Karp… - Journal of Nuclear …, 2006 - Soc Nuclear Med
Despite the increasing use of 18F-FDG PET as a biomarker for predicting therapeutic response,
there are no widely accepted standardized protocols for using 18F-FDG PET as a tool …

Sex differences in regional cerebral glucose metabolism during a resting state

RC Gur, LH Mozley, PD Mozley, SM Resnick, JS Karp… - Science, 1995 - science.org
Positron emission tomography was used to evaluate the regional distribution of cerebral
glucose metabolism in 61 healthy adults at rest. Although the profile of metabolic activity was …

[HTML][HTML] Recent developments in time-of-flight PET

…, E Mikhaylova, E D'Hoe, P Mollet, JS Karp - EJNMMI physics, 2016 - Springer
While the first time-of-flight (TOF)-positron emission tomography (PET) systems were already
built in the early 1980s, limited clinical studies were acquired on these scanners. PET was …