Application of stem cell biology to breast cancer research has been limited by the lack of
simple methods for identification and isolation of normal and malignant stem cells. Utilizing in …

Breast cancer is a heterogeneous disease with varied morphological appearances, molecular
features, behavior, and response to therapy. Current routine clinical management of …

… van de Vijver, Jocelyne Jacquemier, Thomas J. Anderson, Peter P. Osin, Lesley McGuffog,
and Douglas F. … Lakhani SR, Jacquemier J, Sloane JP, et al: Multifactorial analysis of …

PURPOSE Several histologic grading systems have been validated in soft tissue sarcomas (STS),
but no system is currently accepted worldwide. The National Cancer Institute (NCI) …

Background : We have previously demonstrated that breast cancers associated with
inherited BRCA1 and BRCA2 gene mutations differ from each other in their histopathologic …

Breast cancer is a heterogeneous disease encompassing a variety of entities with distinct
morphological features and clinical behaviors. Although morphology is often associated with …

Purpose: To examine the role of cancer stem cells (CSC) in mediating metastasis in
inflammatory breast cancer (IBC) and the association of these cells with patient outcome in this …

Purpose: To investigate the proportion of breast cancers arising in patients with germ line
BRCA1 and BRCA2 mutations expressing basal markers and developing predictive tests for …

PURPOSE To define the prognostic factors in adult patients with locally controlled soft tissue
sarcoma (STS) and to determine which patients should be considered for adjuvant treatment…

Mammary recurrences were studied in 1593 patients with Stage I and II breast cancer
treated by macroscopically complete tumor excision followed by megavoltage radiotherapy, …