Genetically encoded contrast in photoacoustic imaging (PAI) is complementary to the intrinsic
contrast provided by endogenous absorbing chromophores such as hemoglobin. The use …

Optoacoustic tomography is a fast developing imaging modality, combining the high contrast
available from optical excitation of tissue with the high resolution and penetration depth of …

Acoustic resolution photoacoustic Doppler velocimetry promises to overcome the spatial
resolution and depth penetration limitations of current blood flow measuring methods. Despite …

Photoacoustic tomography (PAT) is intrinsically sensitive to blood oxygen saturation (sO 2 )
in vivo. However, making accurate sO 2 measurements without knowledge of tissue- and …

The feasibility of making spatially resolved measurements of blood velocity using a pulsed
photoacoustic Doppler technique in acoustic resolution mode has been investigated. Doppler …

Optoacoustic tomography (OT) is now widely used in preclinical imaging; however, the
precision (repeatability and reproducibility) of OT has yet to be determined. Methods: We used a …

The tumour microenvironment (TME) is a complex cellular ecosystem subjected to chemical
and physical signals that play a role in shaping tumour heterogeneity, invasion and …

Background Optoacoustic tomography (OT) of breast tumour oxygenation is a promising
new technique, currently in clinical trials, which may help to determine disease stage and …

Significance: Photoacoustic imaging (PAI) enables the detection of blood hemoglobin (HB)
concentration and oxygenation (sO 2 ) with high contrast and resolution. Despite the heavy …

Photoacoustic Doppler velocimetry provides a major opportunity to overcome limitations of
existing blood flow measuring methods. By enabling measurements with high spatial …