Stereotactic ablative radiotherapy versus lobectomy for operable stage I non-small-cell lung cancer: a pooled analysis of two randomised trials

…, P Balter, HJM Groen, SE McRae, J Widder… - The lancet …, 2015 - thelancet.com
Background The standard of care for operable, stage I, non-small-cell lung cancer (NSCLC)
is lobectomy with mediastinal lymph node dissection or sampling. Stereotactic ablative …

[HTML][HTML] Selection of patients for radiotherapy with protons aiming at reduction of side effects: the model-based approach

…, P Lambin, D De Ruysscher, J Widder… - Radiotherapy and …, 2013 - Elsevier
Most new radiation techniques, have been introduced primarily to reduce the dose to normal
tissues in order to prevent radiation-induced side effects. Radiotherapy with protons is such …

Role of radiotherapy fractionation in head and neck cancers (MARCH): an updated meta-analysis

…, V Torri, L Tripcony, J Waldron, J Widder… - The Lancet …, 2017 - thelancet.com
Background The Meta-Analysis of Radiotherapy in squamous cell Carcinomas of Head and
neck (MARCH) showed that altered fractionation radiotherapy is associated with improved …

[HTML][HTML] Practice recommendations for lung cancer radiotherapy during the COVID-19 pandemic: An ESTRO-ASTRO consensus statement

…, BJ Slotman, M Stuschke, G Videtic, J Widder… - Radiotherapy and …, 2020 - Elsevier
Background The COVID-19 pandemic has caused radiotherapy resource pressures and led
to increased risks for lung cancer patients and healthcare staff. An international group of …

[HTML][HTML] Recommendations for implementing stereotactic radiotherapy in peripheral stage IA non-small cell lung cancer: report from the Quality Assurance Working …

…, JP Cuijpers, FJ Lagerwaard, J Widder… - Radiation …, 2009 - Springer
Background A phase III multi-centre randomised trial (ROSEL) has been initiated to establish
the role of stereotactic radiotherapy in patients with operable stage IA lung cancer. Due to …

[HTML][HTML] Micro-and nanoplastics breach the blood–brain barrier (BBB): Biomolecular corona's role revealed

…, K Wen, T Kovács, AS Keimowitz, V Pichler, J Widder… - Nanomaterials, 2023 - mdpi.com
Humans are continuously exposed to polymeric materials such as in textiles, car tires and
packaging. Unfortunately, their break down products pollute our environment, leading to …

Metastases-directed stereotactic body radiotherapy in combination with targeted therapy or immunotherapy: systematic review and consensus recommendations by …

…, P Westhoff, J But-Hadzic, J Widder… - The lancet …, 2023 - thelancet.com
Stereotactic body radiotherapy (SBRT) for patients with metastatic cancer, especially when
characterised by a low tumour burden (ie, oligometastatic disease), receiving targeted …

Pulmonary oligometastases: metastasectomy or stereotactic ablative radiotherapy?

J Widder, TJ Klinkenberg, JF Ubbels… - Radiotherapy and …, 2013 - Elsevier
Background and purpose Stereotactic ablative radiotherapy (SABR; or stereotactic body
radiotherapy, SBRT) emerges as treatment option for pulmonary oligometastatic disease (OMD)…

Is cardiac toxicity a relevant issue in the radiation treatment of esophageal cancer?

JC Beukema, P van Luijk, J Widder… - Radiotherapy and …, 2015 - Elsevier
Purpose: In recent years several papers have been published on radiation-induced cardiac
toxicity, especially in breast cancer patients. However, in esophageal cancer patients the …

The quest for evidence for proton therapy: model-based approach and precision medicine

J Widder, A Van Der Schaaf, P Lambin… - International Journal of …, 2016 - Elsevier
Purpose Reducing dose to normal tissues is the advantage of protons versus photons. We
aimed to describe a method for translating this reduction into a clinically relevant benefit. …