… Here, we extend those findings of Sojkova and colleagues [37] by examining the
correspondence between regional PiB retention (as opposed to mean cortical DVR) with region-…

Background In demented older adults, in vivo amyloid imaging shows agreement with
diagnostic neuropathologic assessment of β-amyloid (Aβ). However, the extent of agreement in …

… Drafting of the manuscript: Sojkova and Wong. Critical revision of the manuscript for
important intellectual content: Zhou, An, Kraut, Ferrucci, Wong, and Resnick. Statistical analysis: …

Alterations to myelin may be a core pathological feature of neurodegenerative diseases.
Although white matter microstructural differences have been described in Parkinson's disease (…

BACKGROUND: The rs3818361 single nucleotide polymorphism in complement component
(3b/4b) receptor-1 (CR1) is associated with increased risk of Alzheimer's disease (AD). …

Although cerebral amyloid deposition may precede cognitive impairment by decades, the
relationship between amyloid deposition and longitudinal change in neuronal function has not, …

Blood-based markers reflecting core pathological features of Alzheimer's disease (AD) in
pre-symptomatic individuals are likely to accelerate the development of disease-modifying …

Postmortem studies of Parkinson's disease (PD) suggest that Lewy body pathology accumulates
in a predictable topographical sequence, beginning in the olfactory bulb, followed by …

Background and Purpose—The relationship between the thickness of the carotid intima (IMT)
and brain function remains unclear in those without clinical manifestations of …

Background and Purpose— The Framingham Heart Study group cardiovascular disease risk
profile (FCRP) score was used to assess the relationship between baseline cardiovascular …