Purpose [ 11 C]PIB and [ 18 F]FDDNP are PET tracers for in vivo detection of the neuropathology
underlying Alzheimer’s disease (AD). [ 18 F]FDG is a glucose analogue and its uptake …

Objective To investigate the association between visit-to-visit variability in blood pressure
and cognitive function in old age (>70 years). Design Prospective cohort study. Setting …

Several methods are in use for analyzing 11 C-Pittsburgh compound-B ( 11 C-PiB) data.
The objective of this study was to identify the method of choice for measuring longitudinal …

… Author Contributions: Dr Moonen and Ms Foster-Dingley contributed equally. Dr Moonen
and Ms Foster-Dingley had full access to all the data in the study and take responsibility for the …

Background The aim of the present study was to investigate microglia activation over time
following traumatic brain injury (TBI) and to relate these findings to glutamate release. …

Introduction: The global disease burden of major depressive disorder urgently requires
prevention in high-risk individuals, such as recently discovered insomnia subtypes. Previous …

Background: the relationship between antihypertensive medication and orthostatic hypotension
in older persons remains ambiguous, due to conflicting observational evidence and lack …

Insomnia Disorder (ID) is the second-most common mental disorder and has a far-reaching
impact on daytime functioning. A meta-analysis indicates that, of all cognitive domains, …

Objective The Geriatric Depression Scale (GDS)‐3A, a three‐item subset of the GDS‐15, is
increasingly used as a measure for apathy in research settings to assess factors associating …

Neuroimaging and genetics studies have advanced our understanding of the neurobiology
of sleep and its disorders. However, individual studies usually have limitations to identifying …