Preclinical evaluation of 18F-PSMA-1007, a new prostate-specific membrane antigen ligand for prostate cancer imaging
J Cardinale, M Schäfer, M Benešová… - Journal of Nuclear …, 2017 - Soc Nuclear Med
In recent years, several radiotracers targeting the prostate-specific membrane antigen (PSMA)
have been introduced. Some of them have had a high clinical impact on the treatment of …
have been introduced. Some of them have had a high clinical impact on the treatment of …
18F-Labelled PSMA-1007 shows similarity in structure, biodistribution and tumour uptake to the theragnostic compound PSMA-617
FL Giesel, J Cardinale, M Schäfer, O Neels… - European journal of …, 2016 - Springer
The biochemical and radiological responses to radionuclide therapy with 177Lu-PSMA-617
targeting prostate-specific membrane antigen (PSMA) make it a promising approach to the …
targeting prostate-specific membrane antigen (PSMA) make it a promising approach to the …
[HTML][HTML] Procedures for the GMP-Compliant Production and Quality Control of [18F]PSMA-1007: A Next Generation Radiofluorinated Tracer for the Detection of …
J Cardinale, R Martin, Y Remde, M Schäfer… - Pharmaceuticals, 2017 - mdpi.com
Radiolabeled tracers targeting the prostate-specific membrane antigen (PSMA) have become
important radiopharmaceuticals for the PET-imaging of prostate cancer. In this connection, …
important radiopharmaceuticals for the PET-imaging of prostate cancer. In this connection, …
Intraindividual comparison of 18F-PSMA-1007 PET/CT, multiparametric MRI, and radical prostatectomy specimens in patients with primary prostate cancer: a …
…, M Schäfer, OC Neels, J Cardinale… - Journal of Nuclear …, 2017 - Soc Nuclear Med
68 Ga-prostate-specific membrane antigen (PSMA)-11 PET/CT represents an advanced
method for the staging of primary prostate cancer (PCa) and diagnosis of recurrent or metastatic …
method for the staging of primary prostate cancer (PCa) and diagnosis of recurrent or metastatic …
An overview of PET radiochemistry, part 2: Radiometals
M Brandt, J Cardinale, ML Aulsebrook… - Journal of Nuclear …, 2018 - Soc Nuclear Med
This continuing educational review provides an overview on radiometals used for PET.
General aspects of radiometal-based radiotracers are covered, and the most frequently applied …
General aspects of radiometal-based radiotracers are covered, and the most frequently applied …
[HTML][HTML] 18F-PSMA-1007 PET/CT detects micrometastases in a patient with biochemically recurrent prostate cancer
FL Giesel, C Kesch, M Yun, J Cardinale… - Clinical Genitourinary …, 2017 - Elsevier
In this case report fluorine-18 (18 F)–prostate-specific membrane antigen (PSMA)-1007
positron emission tomography (PET)/computed tomography imaging was performed, to our …
positron emission tomography (PET)/computed tomography imaging was performed, to our …
Development of PSMA-1007-Related Series of 18F-Labeled Glu-Ureido-Type PSMA Inhibitors
J Cardinale, M Roscher, M Schäfer… - Journal of medicinal …, 2020 - ACS Publications
In recent years, a number of drugs targeting the prostate-specific membrane antigen (PSMA)
have become important tools in the diagnosis and treatment of prostate cancer. In the …
have become important tools in the diagnosis and treatment of prostate cancer. In the …
FAPI PET: fibroblast activation protein inhibitor use in oncologic and nononcologic disease
Y Mori, K Dendl, J Cardinale, C Kratochwil, FL Giesel… - Radiology, 2023 - pubs.rsna.org
Gallium 68 ( 68 Ga)–labeled fibroblast activation protein (FAP) inhibitor (FAPI) PET is based
on the molecular targeting of the FAP, which is known to be highly expressed in the major …
on the molecular targeting of the FAP, which is known to be highly expressed in the major …
[HTML][HTML] Head-to-head intra-individual comparison of biodistribution and tumor uptake of 68Ga-FAPI and 18F-FDG PET/CT in cancer patients
…, T Lindner, SA Koerber, J Cardinale… - European journal of …, 2021 - Springer
Purpose FAPI ligands (fibroblast activation protein inhibitor), a novel class of radiotracers for
PET/CT imaging, demonstrated in previous studies rapid and high tumor uptake. The …
PET/CT imaging, demonstrated in previous studies rapid and high tumor uptake. The …
[HTML][HTML] FAP and FAPI-PET/CT in malignant and non-malignant diseases: a perfect symbiosis?
K Dendl, SA Koerber, C Kratochwil, J Cardinale… - Cancers, 2021 - mdpi.com
Simple Summary FAPI represents a novel class of radiotracers demonstrating promising
results in terms of a high uptake in concordance with low background noise in several …
results in terms of a high uptake in concordance with low background noise in several …