Adoptive transfer of large numbers of tumor-reactive CD8 + cytotoxic T lymphocytes (CTLs)
expanded and differentiated in vitro has shown promising clinical activity against cancer. …

The development of molecularly targeted probes that exhibit high biostability, biocompatibility,
and efficient clearance profiles is key to optimizing biodistribution and transport across …

Two genetic reporter systems were developed for multimodality reporter gene imaging of
different molecular-genetic processes using fluorescence, bioluminescence (BLI), and nuclear …

Recent studies show that edible berries may have potent chemopreventive properties. Anti-angiogenic
approaches to prevent and treat cancer represent a priority area in investigative …

Activated NF-κB is a critical mechanism by which lymphoma cells infected by Epstein-Barr
virus (EBV/HHV-4) and Kaposi sarcoma herpesvirus (KSHV/HHV-8) are protected from …

The relationship between exhaustive exercise, oxidative stress, the protective capacity of
the antioxidant defense system and cellular immune response has been determined. …

Tumor hypoxia is a spatially and temporally heterogeneous phenomenon, which results
from several tumor and host tissue-specific processes. To study the dynamics and spatial …

Bone marrow–derived endothelial progenitor cells (EPC) contribute to the angiogenesis-dependent
growth of tumors in mice and humans. EPCs regulate the angiogenic switch via …

Purpose: We compared the metabolic profiles and the association between LDH-A expression
and lactate production in two isogenic murine breast cancer cell lines and tumors (67NR …

Transcription factors are important targets for the treatment of a variety of malignancies but
are extremely difficult to inhibit, as they are located in the cell's nucleus and act mainly by …