Malignant gliomas are the most common and deadly brain tumors. Nevertheless, survival for
patients with glioblastoma, the most aggressive glioma, although individually variable, has …

Purpose: To determine the antitumor efficacy and safety profile of temozolomide in patients
with malignant astrocytoma at first relapse. Patients and Methods: This open-label, …

Question Should patients with newly-diagnosed metastatic brain tumors undergo stereotactic
radiosurgery (SRS) compared with other treatment modalities? Target population These …

Question Should patients with newly-diagnosed metastatic brain tumors undergo open surgical
resection versus whole brain radiation therapy (WBRT) and/or other treatment modalities …

Background Patients with incomplete surgical resection of medulloblastoma are controversially
regarded as having a marker of high-risk disease, which leads to patients undergoing …

The development of targeted anti-cancer therapies through the study of cancer genomes is
intended to increase survival rates and decrease treatment-related toxicity. We treated a …

Should whole brain radiation therapy (WBRT) be used as the sole therapy in patients with
newly-diagnosed, surgically accessible, single brain metastases, compared with WBRT plus …

Question Do steroids improve neurologic symptoms in patients with metastatic brain tumors
compared to no treatment? If steroids are given, what dose should be used? Comparisons …

Object. Catheter-related infection of the cerebrospinal fluid (CSF) pathways is a potentially
life-threatening complication of external ventricular drainage. A major source of infection is …

Metastatic tumours involving the brain overshadow primary brain neoplasms in frequency
and are an important complication in the overall management of many cancers. Importantly, …