User profiles for Jeffrey Lee

Jeffrey E Lee

Professor of Surgery, University of Texas MD Anderson Cancer Center
Verified email at mdanderson.org
Cited by 73465

Systematic variation in gene expression patterns in human cancer cell lines

…, CM Perou, C Rees, P Spellman, V Iyer, SS Jeffrey… - Nature …, 2000 - nature.com
We used cDNA microarrays to explore the variation in expression of approximately 8,000
unique genes among the 60 cell lines used in the National Cancer Institute's screen for anti-…

EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy

JG Paez, PA Janne, JC Lee, S Tracy, H Greulich… - Science, 2004 - science.org
Receptor tyrosine kinase genes were sequenced in non–small cell lung cancer (NSCLC)
and matched normal tissue. Somatic mutations of the epidermal growth factor receptor gene …

[PDF][PDF] Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis

…, JJ Clark, S Moore, J Adelsperger, S Koo, JC Lee… - Cancer cell, 2005 - cell.com
Polycythemia vera (PV), essential thrombocythemia (ET), and myeloid metaplasia with
myelofibrosis (MMM) are clonal disorders arising from hematopoietic progenitors. An internet-…

The transcriptional program in the response of human fibroblasts to serum

…, MB Eisen, DT Ross, G Schuler, T Moore, JCF Lee… - science, 1999 - science.org
The temporal program of gene expression during a model physiological response of human
cells, the response of fibroblasts to serum, was explored with a complementary DNA …

Distinctive gene expression patterns in human mammary epithelial cells and breast cancers

CM Perou, SS Jeffrey, M Van De Rijn… - Proceedings of the …, 1999 - National Acad Sciences
cDNA microarrays and a clustering algorithm were used to identify patterns of gene
expression in human mammary epithelial cells growing in culture and in primary human breast …

[BOOK][B] Manifolds and differential geometry

JM Lee - 2022 - books.google.com
Differential geometry began as the study of curves and surfaces using the methods of calculus.
In time, the notions of curve and surface were generalized along with associated notions …

[PDF][PDF] Multi-institutional melanoma lymphatic mapping experience: the prognostic value of sentinel lymph node status in 612 stage I or II melanoma patients

…, JE Lee, MI Colome, C Tseng, JJ Lee… - Journal of clinical …, 1999 - Citeseer
Purpose: To compare the effect of pathologic sentinel lymph node (SLN) status with that of
other known prognostic factors on recurrence and survival in patients with stage I or II …

Dietary fiber and probiotics influence the gut microbiome and melanoma immunotherapy response

…, MA Davies, MI Ross, JE Gershenwald, JE Lee… - Science, 2021 - science.org
Gut bacteria modulate the response to immune checkpoint blockade (ICB) treatment in cancer,
but the effect of diet and supplements on this interaction is not well studied. We assessed …

B cells and tertiary lymphoid structures promote immunotherapy response

…, FG Kugeratski, S Patel, MA Davies, P Hwu, JE Lee… - Nature, 2020 - nature.com
Abstract Treatment with immune checkpoint blockade (ICB) has revolutionized cancer therapy.
Until now, predictive biomarkers 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 – 10 and strategies to augment …

[HTML][HTML] Adenoma detection rate and risk of colorectal cancer and death

…, CD Jensen, AR Marks, WK Zhao, JK Lee… - New england journal …, 2014 - Mass Medical Soc
Background The proportion of screening colonoscopic examinations performed by a
physician that detect one or more adenomas (the adenoma detection rate) is a recommended …