An assessment of the effects of shell cross-linked nanoparticle size, core composition, and surface PEGylation on in vivo biodistribution

X Sun, R Rossin, JL Turner, ML Becker… - …, 2005 - ACS Publications
Amphiphilic core−shell nanoparticles have drawn considerable interest in biomedical
applications. The precise control over their physicochemical parameters and the ability to attach …

64Cu-labeled folate-conjugated shell cross-linked nanoparticles for tumor imaging and radiotherapy: synthesis, radiolabeling, and biologic evaluation

R Rossin, D Pan, K Qi, JL Turner, X Sun… - Journal of Nuclear …, 2005 - Soc Nuclear Med
Long-circulating nanoparticles functionalized with ligands for receptors overexpressed by
tumor cells have promising applications for active and passive tumor targeting. The purpose of …

Fabrication of hybrid nanocapsules by calcium phosphate mineralization of shell cross-linked polymer micelles and nanocages

KK Perkin, JL Turner, KL Wooley, S Mann - Nano Letters, 2005 - ACS Publications
Self-assembled shell cross-linked poly(acrylic acid-b-isoprene) (PAA 78 -b-PI 97 ) micelles
or cross-linked PAA nanocages in aqueous solution were used as templates for the …

Folic acid-conjugated nanostructured materials designed for cancer cell targeting

D Pan, JL Turner, KL Wooley - Chemical communications, 2003 - pubs.rsc.org
Shell cross-linked nanoparticles (SCKs) constitute a unique class of materials with amphiphilic
core-shell morphology; SCKs are characterised by their structural integrity and available …

Synthesis of gadolinium‐labeled shell‐crosslinked nanoparticles for magnetic resonance imaging applications

JL Turner, D Pan, R Plummer, Z Chen… - Advanced Functional …, 2005 - Wiley Online Library
Shell‐crosslinked knedel‐like nanoparticles (SCKs; “knedel” is a Polish term for dumplings)
were derivatized with gadolinium chelates and studied as robust magnetic‐resonance‐…

Shell Cross-Linked Nanoparticles Designed To Target Angiogenic Blood Vessels via αvβ3 Receptor−Ligand Interactions

D Pan, JL Turner, KL Wooley - Macromolecules, 2004 - ACS Publications
The design, synthesis, and characterization of a novel polymeric nanostructured material
bearing surface-attached integrin antagonists are demonstrated. The covalent coupling of a …

Nanoscale cage-like structures derived from polyisoprene-containing shell cross-linked nanoparticle templates

JL Turner, KL Wooley - Nano letters, 2004 - ACS Publications
Hollowed materials of nanoscopic dimensions offer exciting possibilities in a number of
fields such as therapeutics and imaging. The production of nanoscopic cage-like materials is …

Regiochemical functionalization of a nanoscale cage-like structure: robust core-shell nanostructures crafted as vessels for selective uptake and release of small and …

JL Turner, Z Chen, KL Wooley - Journal of controlled release, 2005 - Elsevier
As synthetic methods evolve toward the preparation of increasingly complex nanostructured
materials inspired from biological nano-objects, the ability to tailor the three-dimensional …

Gemcitabine-associated thrombotic microangiopathy: response to complement inhibition and reinitiation of gemcitabine

JL Turner, J Reardon, T Bekaii-Saab… - Clinical colorectal …, 2017 - Elsevier
Gemcitabine is a pyrimidine analogue that is a standard-of-care treatment for both resectable
and unresectable pancreatic cancer. 1 Since its initial use in clinical trials, there are many …

IDPQuantify: combining precursor intensity with spectral counts for protein and peptide quantification

…, MC Chambers, M Li, AJL Ham, JL Turner… - Journal of Proteome …, 2013 - ACS Publications
Differentiating and quantifying protein differences in complex samples produces significant
challenges in sensitivity and specificity. Label-free quantification can draw from two different …