Alternative processing of the RNA transcribed from the calcitonin gene appears to result in the
production of a messenger RNA in neural tissue distinct from that in thyroidal ‘C’ cells. The …

A peptide with high potency and intrinsic activity for stimulating the secretion of corticotropin-like
and β-endorphin-like immunoactivities by cultured anterior pituitary cells has been …

A peptide has been isolated from ovine hypothalamus which, at 1 × 10 -9 M, inhibits secretion
in vitro of immunoreactive rat or human growth hormones and is similarly active in vivo in …

The distribution of corticotropin-releasing factor (CRF)-immunoreactive cells and fibers has
been examined in the brains of normal adult rats, and in the brains of animals that had been …

CORTICOTROPIN-RELEASING factor (CRF), a peptide first isolated from mammalian brain
1 , is critical in the regulation of the pituitary–adrenal axis, and in complementary stress-…

A variety of hypophysiotropic peptides or proteins have been reported to be present in
mammalian gonads. Inhibin, a hormone that under most circumstances selectively suppresses the …

The neuroregulation of growth hormone (GH) secretion is mediated in part by a stimulatory,
GH-releasing factor (GRF) and an inhibitory peptide, somatostatin 1 , both of which reach the …

Amyloids are highly organized cross–β-sheet–rich protein or peptide aggregates that are
associated with pathological conditions including Alzheimer’s disease and type II diabetes. …

To paralyze their more agile prey, the venomous fish-hunting cone snails (Conus) have
developed a potent biochemical strategy. They produce several classes of toxic peptides (…

A 41-residue peptide with high potency and intrinsic activity to stimulate the secretion of
corticotropin and β-endorphin by the adenohypophysis has been characterized and synthesized …