The rsna-asnr-miccai brats 2021 benchmark on brain tumor segmentation and radiogenomic classification

…, J Mongan, C Hess, S Cha, J Villanueva-Meyer… - arXiv preprint arXiv …, 2021 - arxiv.org
The BraTS 2021 challenge celebrates its 10th anniversary and is jointly organized by the
Radiological Society of North America (RSNA), the American Society of Neuroradiology (ASNR…

[HTML][HTML] Federated learning enables big data for rare cancer boundary detection

…, E Calabrese, J Rudie, J Villanueva-Meyer… - Nature …, 2022 - nature.com
Although machine learning (ML) has shown promise across disciplines, out-of-sample
generalizability is concerning. This is currently addressed by sharing multi-site data, but such …

Meningioma DNA methylation groups identify biological drivers and therapeutic vulnerabilities

…, HN Vasudevan, SJ Liu, JE Villanueva-Meyer… - Nature …, 2022 - nature.com
Meningiomas are the most common primary intracranial tumors. There are no effective
medical therapies for meningioma patients, and new treatments have been encumbered by …

Frontal lobe degeneration: clinical, neuropsychological, and SPECT characteristics

BL Miller, JL Cummings, J Villanueva-Meyer, K Boone… - Neurology, 1991 - AAN Enterprises
The clinical, neuropsychological, and cerebral blood flow characteristics of eight patients
with frontal lobe degeneration (FLD) were studied. Social withdrawal and behavioral …

Association of maximal extent of resection of contrast-enhanced and non–contrast-enhanced tumor with survival within molecular subgroups of patients with newly …

…, J Eckel-Passow, R Jenkins, J Villanueva-Meyer… - JAMA …, 2020 - jamanetwork.com
Importance Per the World Health Organization 2016 integrative classification, newly
diagnosed glioblastomas are separated into isocitrate dehydrogenase gene 1 or 2 (IDH)–wild-type …

Current clinical brain tumor imaging

JE Villanueva-Meyer, MC Mabray, S Cha - Neurosurgery, 2017 - journals.lww.com
Neuroimaging plays an ever evolving role in the diagnosis, treatment planning, and post-therapy
assessment of brain tumors. This review provides an overview of current magnetic …

Detailed comparison of amyloid PET and CSF biomarkers for identifying early Alzheimer disease

…, K Johnson, RS Doody, J Villanueva-Meyer… - Neurology, 2015 - AAN Enterprises
Objective: To compare the diagnostic accuracy of CSF biomarkers and amyloid PET for
diagnosing early-stage Alzheimer disease (AD). Methods: From the prospective, longitudinal …

A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderly

…, RS Doody, J Villanueva-Meyer… - Proceedings of the …, 2010 - National Acad Sciences
A recently identified variant within the fat mass and obesity-associated (FTO) gene is carried
by 46% of Western Europeans and is associated with an ~1.2 kg higher weight, on average, …

Hyperpolarized 13C MRI: State of the Art and Future Directions

…, JW Gordon, RA Bok, J Slater, JE Villanueva-Meyer… - Radiology, 2019 - pubs.rsna.org
Hyperpolarized (HP) carbon 13 ( 13 C) MRI is an emerging molecular imaging method that
allows rapid, noninvasive, and pathway-specific investigation of dynamic metabolic and …

PET/MRI: where might it replace PET/CT?

…, GB Johnson, JE VillanuevaMeyer… - Journal of Magnetic …, 2017 - Wiley Online Library
Simultaneous positron emission tomography and MRI (PET/MRI) is a technology that
combines the anatomic and quantitative strengths of MR imaging with physiologic information …