89 Zr (half-life, 78.41 h) is a positron-emitting radionuclide that displays excellent potential
for use in the design and synthesis of radioimmunoconjugates for immunoPET. In the current …

Zirconium-89 is an attractive metallo-radionuclide for use in immuno-PET due to favorable
decay characteristics. Standardized methods for the routine production and isolation of high-…

The development of novel multimodality imaging agents and techniques represents the current
frontier of research in the field of medical imaging science. However, the combination of …

Rapid and widespread growth in the use of nuclear medicine for both diagnosis and therapy
of disease has been the driving force behind burgeoning research interests in the design of …

Single wall carbon nanotube (SWCNT) constructs were covalently appended with
radiometal-ion chelates (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid [DOTA] or …

Targeted nanoparticle-based technologies show increasing prevalence in radiotracer
design. As a consequence, quantitative contribution of nonspecific accumulation in the target …

Palladium-catalyzed terminal alkyne dimerization, through oxidative homocoupling, is a
useful approach to the synthesis of symmetrical 1,4-diynes. Recent investigations have …

Purpose Given the bone tropism of prostate cancer, conventional imaging modalities poorly
identify or quantify metastatic disease. Zr-huJ591 positron emission tomography (PET) …

Background The positron-emitting radionuclide 89 Zr (t 1/2 = 3.17 days) was used to
prepare 89 Zr-radiolabeled trastuzumab for use as a radiotracer for characterizing HER2/neu-…

Two new types of unsymmetrical bis(thiosemicarbazone) proligands and their neutral zinc(II)
and copper(II) complexes have been synthesized. These bifunctional ligands both chelate …