User profiles for Jason Kovacic
Jason C Kovacic | MBBS, PhD, FRACP, FACC, FSCAI, FAHAVictor Chang Cardiac Research Institute Verified email at victorchang.edu.au Cited by 13257 |
[HTML][HTML] Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability
…, R Hajjar, V Fuster, M Boehm, JC Kovacic - Nature …, 2016 - nature.com
Endothelial to mesenchymal transition (EndMT) plays a major role during development, and
also contributes to several adult cardiovascular diseases. Importantly, mesenchymal cells …
also contributes to several adult cardiovascular diseases. Importantly, mesenchymal cells …
Epithelial-to-mesenchymal and endothelial-to-mesenchymal transition: from cardiovascular development to disease
JC Kovacic, N Mercader, M Torres, M Boehm… - Circulation, 2012 - Am Heart Assoc
Cellular switching from an epithelial-to-mesenchymal phenotype, and conversely from a
mesenchymal-toepithelial phenotype, are important biological programs that are operative from …
mesenchymal-toepithelial phenotype, are important biological programs that are operative from …
TGF-β signaling mediates endothelial-to-mesenchymal transition (EndMT) during vein graft remodeling
…, R Feil, R Virmani, E Ladich, JC Kovacic… - Science translational …, 2014 - science.org
Veins grafted into an arterial environment undergo a complex vascular remodeling process.
Pathologic vascular remodeling often results in stenosed or occluded conduit grafts. …
Pathologic vascular remodeling often results in stenosed or occluded conduit grafts. …
Endothelial to Mesenchymal Transition in Cardiovascular Disease: JACC State-of-the-Art Review
Endothelial to mesenchymal transition (EndMT) is a process whereby an endothelial cell
undergoes a series of molecular events that lead to a change in phenotype toward a …
undergoes a series of molecular events that lead to a change in phenotype toward a …
Cellular senescence, vascular disease, and aging: part 2 of a 2-part review: clinical vascular disease in the elderly
JC Kovacic, P Moreno, EG Nabel, V Hachinski… - Circulation, 2011 - Am Heart Assoc
The increasing prevalence of older-age people in our society represents the culmination of
centuries of medical, scientific, and social endeavors. At least in Western society, now …
centuries of medical, scientific, and social endeavors. At least in Western society, now …
Impact of oxidative stress on the heart and vasculature: part 2 of a 3-part series
Vascular disease and heart failure impart an enormous burden in terms of global morbidity
and mortality. Although there are many different causes of cardiac and vascular disease, …
and mortality. Although there are many different causes of cardiac and vascular disease, …
First international consensus on the diagnosis and management of fibromuscular dysplasia
…, D Kadian-Dodov, ESH Kim, JC Kovacic… - Vascular …, 2019 - journals.sagepub.com
This article is a comprehensive document on the diagnosis and management of fibromuscular
dysplasia (FMD), which was commissioned by the working group ‘Hypertension and the …
dysplasia (FMD), which was commissioned by the working group ‘Hypertension and the …
Oxidative stress and cardiovascular risk: obesity, diabetes, smoking, and pollution: part 3 of a 3-part series
…, MR Miller, DE Newby, V Fuster, JC Kovacic - Journal of the American …, 2017 - jacc.org
Oxidative stress occurs whenever the release of reactive oxygen species (ROS) exceeds
endogenous antioxidant capacity. In this paper, we review the specific role of several …
endogenous antioxidant capacity. In this paper, we review the specific role of several …
Colchicine in cardiovascular disease: in-depth review
Inflammation plays a prominent role in the development of atherosclerosis and other
cardiovascular diseases, and anti-inflammatory agents may improve cardiovascular outcomes. For …
cardiovascular diseases, and anti-inflammatory agents may improve cardiovascular outcomes. For …
Impact of the everolimus-eluting stent on stent thrombosis: a meta-analysis of 13 randomized trials
…, MC Kim, J Suleman, R Pyo, J Wiley, J Kovacic… - Journal of the American …, 2011 - jacc.org
Objectives : We evaluated the impact of the everolimus-eluting stent (EES) on the frequency
of stent thrombosis (ST), target vessel revascularization (TVR), myocardial infarction (MI), …
of stent thrombosis (ST), target vessel revascularization (TVR), myocardial infarction (MI), …