Efficacy of nivolumab and AVD in early-stage unfavorable classic Hodgkin lymphoma: the randomized phase 2 German Hodgkin Study Group NIVAHL trial

…, M Bormann, A Zimmermann, J Mettler… - JAMA …, 2020 - jamanetwork.com
Importance In early-stage unfavorable classic Hodgkin lymphoma (cHL), conventional therapy
induces high cure rates but also relevant acute and long-term toxic effects. Nivolumab is …

Metabolic tumor volume for response prediction in advanced-stage Hodgkin lymphoma

J Mettler, H Müller, CA Voltin, C Baues… - Journal of Nuclear …, 2019 - Soc Nuclear Med
18 F-FDG PET/CT for staging Hodgkin lymphoma may allow for accurate and reliable assessment
of the metabolic tumor volume (MTV) as a baseline risk factor. Our aim was to analyze …

[HTML][HTML] Predictive value of baseline metabolic tumor volume in early-stage favorable Hodgkin Lymphoma–Data from the prospective, multicenter phase III HD16 trial

L van Heek, C Stuka, H Kaul, H Müller, J Mettler, F Hitz… - BMC cancer, 2022 - Springer
Background 18 F -fluorodeoxyglucose (FDG) positron emission tomography (PET) plays an
important role in the staging and response assessment of lymphoma patients. Our aim was …

[HTML][HTML] FDG-PET Imaging for Hodgkin and Diffuse large B-cell lymphoma—An updated overview

CA Voltin, J Mettler, J Grosse, M Dietlein, C Baues… - Cancers, 2020 - mdpi.com
Since the mid-1990s, 18 F-fluorodeoxglucose (FDG)-positron emission tomography (PET)
in combination with computed tomography has come to play a prominent role in the …

Early response to first-line anti–PD-1 treatment in hodgkin lymphoma: A PET-based analysis from the prospective, randomized phase II NIVAHL trial

CA Voltin, J Mettler, L van Heek, H Goergen… - Clinical Cancer …, 2021 - AACR
Purpose: A primary analysis of the ongoing NIVAHL trial demonstrated unexpectedly high
interim complete response rates to nivolumab-based first-line treatment in early-stage …

Outcome-based interpretation of early interim PET in advanced-stage Hodgkin lymphoma

…, J Zijlstra, O Hoekstra, J Mettler… - Blood, The Journal …, 2018 - ashpublications.org
The HD18 study for patients with newly diagnosed advanced-stage Hodgkin lymphoma (HL)
used positron emission tomography (PET) after 2 cycles (PET-2) of bleomycin, etoposide, …

Prognostic value of baseline metabolic tumor volume (MTV) for forecasting chemotherapy outcome in early‐stage unfavorable Hodgkin lymphoma: Data from the …

…, C Gorniak, H Kaul, H Müller, J Mettler… - European Journal of …, 2023 - Wiley Online Library
Objectives The prognostic relevance of metabolic tumor volume (MTV) having recently been
demonstrated in patients with early‐stage favorable and advanced‐stage Hodgkin …

Quantitative assessment of 18F-FDG PET in patients with Hodgkin lymphoma: is it significantly affected by contrast-enhanced computed tomography attenuation …

CA Voltin, J Mettler, R Boellaard… - Nuclear Medicine …, 2019 - journals.lww.com
Objective The reliability of visual and quantitative response assessment may be impaired
owing to inconsistent scanning protocols and image reconstruction methods of 2-deoxy-2-[18 F…

Avoidance of iodine deficiency/excess during pregnancy in hashimoto's thyroiditis

…, M Faust, C Chiapponi, J Mettler… - Nuklearmedizin …, 2021 - thieme-connect.com
Purpose Hashimoto’s thyroiditis is a common disease that also affects pregnant women. We
analyzed to what extent the inflammatory process of Hashimoto’s thyroiditis changes with …

[HTML][HTML] Metabolic tumor volume for early response assessment in early-stage unfavorable Hodgkin lymphoma treated with nivolumab in the GHSG Nivahl phase II …

CA Voltin, J Mettler, H Mueller, M Fuchs, C Baues… - Blood, 2019 - Elsevier
Background: Metabolic tumor volume (MTV) measured by FDG-PET/CT is becoming established
as an independent risk factor for treatment failure in Hodgkin lymphoma (HL). Moreover…