Brain metastases are an increasingly frequent complication of cancer. Advances in
diagnosis and treatment have led to wider indications for surgery. We present a single-institution …

A characteristic feature of malignant glial tumors (gliomas) is their tendency to diffusely
infiltrate the nervous system preventing their complete surgical resection. Proteases play a …

The molecular regulation of the recruitment of initial signaling complexes at the TNF-R1 is
poorly defined. We demonstrate here that within minutes internalized TNF-R1 (TNF …

… Ole Helm and Janka Held-Feindt equally contributed to this … Ole Helm and Janka Held-Feindt
equally contributed to this … Ole Helm and Janka Held-Feindt equally contributed to this work…

The chemokine CXCL12/stromal cell–derived factor-1 and its receptor CXCR4 play a major
role in tumor invasion, proliferation, and metastasis. Recently, CXCR7 was identified as a …

Angiogenesis, the formation of new blood vessels, is required for the growth and expansion
of tumours. Gliomas, the most common brain tumours, are particularly highly vascularized …

According to new hypotheses astrocytomas/gliomas either arise from or attract neural stem
cells. Biological markers, particularly antigenic markers, have played a significant role for the …

Purpose Brain metastases are an increasingly common complication in breast cancer patients.
The Metastasis Suppressor Genes (MSG) Nm23, KISS1, KAI1, BRMS1, and Mkk4 have …

purpose. Recent studies have reported neuroprotective effects of erythropoietin (EPO) and
vascular endothelial growth factor (VEGF). The purpose of the present study was to clarify …

The transmembrane chemokine CX3CL1 and its receptor CX3CR1 are thought to be
involved in the trafficking of immune cells during an immune response and in the pathology of …