Focal nodular hyperplasia: findings at state-of-the-art MR imaging, US, CT, and pathologic analysis

…, E Lanjouw, S De Rave, JNM IJzermans… - Radiographics, 2004 - pubs.rsna.org
Focal nodular hyperplasia (FNH) is the second most common benign liver tumor after
hemangioma. FNH is classified into two types: classic (80% of cases) and nonclassic (20%). …

Surgery for cholangiocarcinoma

…, F Mocchegiani, HJ Schlitt, JNM Ijzermans… - Liver …, 2019 - Wiley Online Library
Surgical resection is the only potentially curative treatment for patients with cholangiocarcinoma.
For both perihilar cholangiocarcinoma (pCCA) and intrahepatic cholangiocarcinoma (…

Benign versus malignant hepatic nodules: MR imaging findings with pathologic correlation

SM Hussain, PE Zondervan, JNM IJzermans… - Radiographics, 2002 - pubs.rsna.org
According to the currently used nomenclature, there are only two types of hepatocellular
nodular lesions: regenerative lesions and dysplastic or neoplastic lesions. Regenerative …

[HTML][HTML] A comparison of suture repair with mesh repair for incisional hernia

…, MMJ Braaksma, JNM IJzermans… - … England Journal of …, 2000 - Mass Medical Soc
Background Incisional hernia is an important complication of abdominal surgery. Procedures
for the repair of these hernias with sutures and with mesh have been reported, but there is …

[HTML][HTML] Long-term culture of genome-stable bipotent stem cells from adult human liver

…, SJ Boers, H Kemperman, J de Jonge, JNM Ijzermans… - Cell, 2015 - cell.com
Despite the enormous replication potential of the human liver, there are currently no culture
systems available that sustain hepatocyte replication and/or function in vitro. We have shown …

Human primary liver cancer–derived organoid cultures for disease modeling and drug screening

…, RK Praseedom, R Lieshout, JNM IJzermans… - Nature medicine, 2017 - nature.com
Human liver cancer research currently lacks in vitro models that can faithfully recapitulate
the pathophysiology of the original tumor. We recently described a novel, near-physiological …

Tissue-specific mutation accumulation in human adult stem cells during life

…, LJW Van Der Laan, J De Jonge, JNM IJzermans… - Nature, 2016 - nature.com
The gradual accumulation of genetic mutations in human adult stem cells (ASCs) during life
is associated with various age-related diseases, including cancer 1 , 2 . Extreme variation in …

Stereotactic body radiation therapy for primary and metastatic liver tumors: A single institution phase i-ii study

…, RP Brandwijk, C Verhoef, JNM Ijzermans… - Acta …, 2006 - Taylor & Francis
The feasibility, toxicity and tumor response of stereotactic body radiation therapy (SBRT) for
treatment of primary and metastastic liver tumors was investigated. From October 2002 until …

[HTML][HTML] Cholangiocarcinoma landscape in Europe: Diagnostic, prognostic and therapeutic insights from the ENSCCA Registry

…, GL Grazi, A Landa-Magdalena, JNM Ijzermans… - Journal of …, 2022 - Elsevier
Background & Aims Cholangiocarcinoma (CCA) is a rare and heterogeneous biliary cancer,
whose incidence and related mortality is increasing. This study investigates the clinical …

Antibodies against immune checkpoint molecules restore functions of tumor-infiltrating T cells in hepatocellular carcinomas

…, H Dong, K Thielemans, Q Pan, JNM IJzermans… - Gastroenterology, 2017 - Elsevier
… with HCC (as determined by flow cytometric analysis of binding to anti-HLA-A2 antibody)
were pretreated with protein tyrosine kinase inhibitor dasatinib at a final concentration of 50 nM