Inadequate surgical margins represent a high risk for adverse clinical outcome in breast-conserving
therapy (BCT) for early-stage breast cancer. The majority of studies report positive …

Familial adenomatous polyposis (FAP) is an autosomal dominantly inherited disorder, which
results from a germ line mutation in the APC (adenomatous polyposis coli) gene. FAP is …

… Author links open overlay panel Si-Qi Qiu a b c , Guo-Jun Zhang c d , Liesbeth Jansen b ,
Jakob de Vries b , Carolien P. Schröder a , Elisabeth GE de Vries a , Gooitzen M. van Dam b e …

Objective: In this article, we aim to (a) identify distinct trajectories of psychological distress in
the first year after a breast cancer diagnosis in women treated with adjuvant therapy and (b) …

Purpose: To provide proof of principle of safety, breast tumor–specific uptake, and positive
tumor margin assessment of the systemically administered near-infrared fluorescent tracer …

Accurate estimations of lifetime risks of breast and ovarian cancer are crucial for counselling
women from BRCA1/2 families. We therefore determined breast and ovarian cancer …

Vascular endothelial growth factor (VEGF)-A is overexpressed in most malignant and
premalignant breast lesions. VEGF-A can be visualized noninvasively with PET imaging and using …

Background In healthy BRCA1/2 mutation carriers, bilateral risk-reducing mastectomy (BRRM)
strongly reduces the risk of developing breast cancer (BC); however, no clear survival …

During the last decade, the emerging field of molecular fluorescence imaging has led to the
development of tumor-specific fluorescent tracers and an increase in early-phase clinical …

Background Long-term shoulder and arm function following sentinel lymph node biopsy (SLNB)
may surpass that following complete axillary lymph node dissection (CLND) or axillary …