18F-Fluoride PET/CT is highly effective for excluding bone metastases even in patients with equivocal bone scintigraphy

…, ECSC Etchebehere, MF Barboza, J Mengatti… - European journal of …, 2012 - Springer
Purpose Bone scintigraphy (BS) has been used extensively for many years for the diagnosis
of bone metastases despite its low specificity and significant rate of equivocal lesions. F-…

A comparative study of 131I and 177Lu labeled somatostatin analogues for therapy of neuroendocrine tumours

…, MT Colturato, RM Couto, PB Pujatti, J Mengatti… - Applied Radiation and …, 2009 - Elsevier
This work analysed the influence of the chelating group and radioligand on somatostatin
analogues in vivo and in vitro properties. The presence of DOTA in the radioiodinated peptide …

Evaluation and comparison of a new DOTA and DTPA-bombesin agonist in vitro and in vivo in low and high GRPR expressing prostate and breast tumor models

…, JC Burnet, KFM Pasqualoto, J Mengatti… - Applied Radiation and …, 2015 - Elsevier
We evaluated and compared a new bombesin analog [Tyr–Gly 5 , Nle 14 ]-BBN(6–14)
conjugated to DOTA or DTPA and radiolabeled with In-111 in low and high GRPR expressing …

Development of a new bombesin analog radiolabeled with lutetium-177: in vivo evaluation of the biological properties in balb-c mice

…, JS Santos, AVF Massicano, J Mengatti - Cellular and molecular …, 2010 - cellmolbiol.org
In this work we describe the first results of radiolabeling with lutetium-177 (177Lu) and in
vivo biodistribution and pharmacokinetics studies in normal Balb-c mice of a new bombesin …

Preparation of [In-111]-labeled-DTPA-bombesin conjugates at high specific activity and stability: Evaluation of labeling parameters and potential stabilizers

PB Pujatti, AVF Massicano, J Mengatti… - Applied Radiation and …, 2012 - Elsevier
The aim of the present work was to obtain stabilized high specific activity (HSA) 111 In-labeled
bombesin conjugates for preclinical evaluations. Parameters influencing the kinetics of …

[HTML][HTML] Radiolabeled nano-peptides show specificity for an animal model of human PC3 prostate cancer cells

…, GEF Nunez, R Teodoro, AM Moro, J Mengatti - Clinics, 2011 - Elsevier
OBJECTIVES Cancer has been investigated using various pre-targeting techniques or
models focusing on radiobombesin analogues; however, both are not offered together. In this …

Effect of thyroid-stimulating hormone in 68Ga-DOTATATE PET/CT of radioiodine-refractory thyroid carcinoma: a pilot study

…, JL Argenton, AO Santos, J Mengatti… - Nuclear medicine …, 2018 - journals.lww.com
Background Radioiodine-refractory thyroid carcinomas (RAIRs) are characterized by reduced
expression of sodium–iodine symporter, rising serum thyroglobulin levels, and negative …

[HTML][HTML] Development of radioimmunoconjugate for diagnosis and management of head-and-neck subclinical cancer and colorectal carcinoma

…, JJ Silva, CAWV Boas, J Mengatti… - Brazilian Journal of …, 2017 - SciELO Brasil
Scientific innovations in diagnostic methods are important drivers of cancer control and
prevention. Noninvasive imaging of the epidermal growth factor receptor (EGFR) in head-and-…

[HTML][HTML] SPECT/CT with radiolabeled somatostatin analogues in the evaluation of systemic granulomatous infections

…, TF Souza, ML Moretti, MR Resende, J Mengatti… - Radiologia …, 2017 - SciELO Brasil
Objective: To evaluate SPECT/CT with radiolabeled somatostatin analogues (RSAs) in
systemic granulomatous infections in comparison with gallium-67 (67Ga) citrate scintigraphy. …

Radiochemical stability of radiopharmaceutical preparations

…, R Herrerias, CL Zapparoli Junior, J Mengatti… - 2011 - inis.iaea.org
The “in vitro” stability studies of the radiopharmaceutical preparations are an essential
requirement for routine practice in nuclear medicine and are an important parameter for …