Endoscopic detection of dysplasia in patients with Barrett's esophagus using light-scattering spectroscopy

…, SJ Shields, I Itzkan, RR Dasari, J Van Dam… - Gastroenterology, 2000 - Elsevier
Background & Aims: We conducted a study to assess the potential of light-scattering
spectroscopy (LSS), which can measure epithelial nuclear enlargement and crowding, for in situ …

Risk factors for complications after performance of ERCP

…, DR Lichtenstein, FW Ruymann, J Van Dam… - Gastrointestinal …, 2002 - Elsevier
Background: ERCP has become widely available for the diagnosis and treatment of benign
and malignant pancreaticobiliary diseases. In this prospective study, the overall complication …

Diffuse reflectance spectroscopy of human adenomatous colon polyps in vivo

…, R Manoharan, M Fitzmaurice, J Van Dam… - Applied …, 1999 - opg.optica.org
Diffuse reflectance spectra were collected from adenomatous colon polyps (cancer precursors)
and normal colonic mucosa of patients undergoing colonoscopy. We analyzed the data …

Fluorescence, reflectance, and light-scattering spectroscopy for evaluating dysplasia in patients with Barrett's esophagus

I Georgakoudi, BC Jacobson, J Van Dam, V Backman… - Gastroenterology, 2001 - Elsevier
Background & Aims: The aim of this study was to assess the potential of 3 spectroscopic
techniques (fluorescence, reflectance, and light-scattering spectroscopy) individually and in …

Endosonographic features predictive of lymph node metastasis

…, MV Sivak Jr, T Rice, LA Gragg, J Van Dam - Gastrointestinal …, 1994 - Elsevier
Endosonographic features that are thought to characterize lymph node metastasis were
evaluated in 100 patients with esophageal carcinoma. Subjects underwent preoperative …

NAD(P)H and Collagen as in Vivo Quantitative Fluorescent Biomarkers of Epithelial Precancerous Changes

…, CP Crum, CW Boone, RR Dasari, J Van Dam… - Cancer research, 2002 - AACR
During the development of neoplasia, epithelial tissues undergo biochemical and structural
changes that can manifest in tissue fluorescence. There have been several reports on …

Endosonographic differentiation of benign and malignant stromal cell tumors

…, J Scheiman, SL Carpenter, J Van Dam… - Gastrointestinal …, 1997 - Elsevier
Background: Endosonography (EUS) is a valuable technique for diagnosing gastrointestinal
stromal cell tumors. However, EUS features that are predictive of malignancy in these …

Single-fraction stereotactic body radiation therapy and sequential gemcitabine for the treatment of locally advanced pancreatic cancer

…, JM Ford, GA Fisher, PL Kunz, J Van Dam… - International Journal of …, 2011 - Elsevier
PURPOSE: This Phase II trial evaluated the toxicity, local control, and overall survival in
patients treated with sequential gemcitabine and linear accelerator–based single-fraction …

Optical biopsy: a new frontier in endoscopic detection and diagnosis

TD Wang, J Van Dam - Clinical gastroenterology and hepatology, 2004 - Elsevier
Endoscopic diagnosis currently relies on the ability of the operator to visualize abnormal
patterns in the image created by light reflected from the mucosal surface of the gastrointestinal …

A Raman-based endoscopic strategy for multiplexed molecular imaging

…, S Friedland, J Van Dam… - Proceedings of the …, 2013 - National Acad Sciences
Endoscopic imaging is an invaluable diagnostic tool allowing minimally invasive access to
tissues deep within the body. It has played a key role in screening colon cancer and is …