Consensus Nomenclature for in vivo Imaging of Reversibly Binding Radioligands
RB Innis, VJ Cunningham, J Delforge… - Journal of Cerebral …, 2007 - journals.sagepub.com
… Jacques Delforge … The cause of this apparent proportional scaling in k 3 and k 4 is
unknown but has been ascribed to radioligand rebinding in a relatively isolated compartment …
unknown but has been ascribed to radioligand rebinding in a relatively isolated compartment …
Positron emission tomography with 11C CGP-12177 to assess beta-adrenergic receptor concentration in idiopathic dilated cardiomyopathy.
P Merlet, J Delforge, A Syrota, E Angevin, B Maziere… - Circulation, 1993 - Am Heart Assoc
BACKGROUND Positron emission tomography (PET) with 11C-labeled CGP-12177 (CGP)
has been shown to have the potential to noninvasively measure beta-adrenergic receptor …
has been shown to have the potential to noninvasively measure beta-adrenergic receptor …
[PDF][PDF] Cardiac beta-adrenergic receptor density measured in vivo using PET, CGP 12177, and a new graphical method
J Delforge, A Syrota, JP Lançon… - Journal of Nuclear …, 1991 - Soc Nuclear Med
Bernard, Parjs, France complexities ofthe model structure and ofthe experimen tal protocol (6).
This is not always possible if we wish to consider a complex model and ifthe choice of …
This is not always possible if we wish to consider a complex model and ifthe choice of …
Quantification of Benzodiazepine Receptors in Human Brain Using PET, [11C]Flumazenil, and a Single-Experiment Protocol
A kinetic method using a multiinjection protocol, positron emission tomography (PET), and [
11 C]flumazenil as a specific ligand was used to study in vivo the flumazenil-benzodiazepine …
11 C]flumazenil as a specific ligand was used to study in vivo the flumazenil-benzodiazepine …
Identifiability analysis and parameter identification of an in vivo ligand-receptor model from PET data
J Delforge, A Syrota, BM Mazoyer - IEEE transactions on …, 1990 - ieeexplore.ieee.org
The identification of the model parameters from data obtained with a single tracer injection
leads to disappointing numerical results, since most of the parameters have to be considered …
leads to disappointing numerical results, since most of the parameters have to be considered …
Seizure-related short-term plasticity of benzodiazepine receptors in partial epilepsy: a [11C]flumazenil-PET study
…, F Bonnefoi, F Lavenne, F Mauguière, J Delforge… - Brain, 2005 - academic.oup.com
We have undertaken a test–re-test [ 11 C]flumazenil (FMZ) PET study in 10 drug-resistant
epileptic patients, including six with a mesiotemporal epilepsy (MTE), and 10 normal controls, …
epileptic patients, including six with a mesiotemporal epilepsy (MTE), and 10 normal controls, …
Increased myocardial muscarinic receptor density in idiopathic dilated cardiomyopathy: an in vivo PET study
D Le Guludec, A Cohen-Solal, J Delforge, N Delahaye… - Circulation, 1997 - Am Heart Assoc
Background Congestive heart failure is associated with decreased stimulated myocardial
adenylate cyclase activity, increased G i -binding protein, attenuated parasympathetic tone, …
adenylate cyclase activity, increased G i -binding protein, attenuated parasympathetic tone, …
Myocardial muscarinic receptor upregulation and normal response to isoproterenol in denervated hearts by familial amyloid polyneuropathy
N Delahaye, D Le Guludec, S Dinanian, J Delforge… - Circulation, 2001 - Am Heart Assoc
Background— Patients with familial amyloid polyneuropathy, a rare hereditary form of
amyloidosis, have progressive autonomic neuropathy. The disease usually does not induce heart …
amyloidosis, have progressive autonomic neuropathy. The disease usually does not induce heart …
Experimental design optimisation: theory and application to estimation of receptor model parameters using dynamic positron emission tomography
J Delforge, A Syrota, BM Mazoyer - Physics in Medicine & …, 1989 - iopscience.iop.org
The general framework and various criteria for experimental design optimisation are
presented. The methodology is applied to the estimation of receptor-ligand reaction model …
presented. The methodology is applied to the estimation of receptor-ligand reaction model …
Modeling [18F]MPPF Positron Emission Tomography Kinetics for the Determination of 5-Hydroxytryptamine(1A) Receptor Concentration with Multiinjection
…, F Lavenne, L Cinotti, J Delforge… - Journal of Cerebral …, 2002 - journals.sagepub.com
The selectivity of [ 18 F]MPPF (fluorine-18-labeled 4-(2' -methoxyphenyl)-1-[2' -(N-2“-pirydynyl)-p-fluorobenzamido]ethylpiperazine)
for serotonergic 5-hydroxytryptamine(1A) (5-HT 1A ) …
for serotonergic 5-hydroxytryptamine(1A) (5-HT 1A ) …