Optimal quality 131I-monoclonal antibodies on high-dose labeling in a large reaction volume and temporarily coating the antibody with IODO-GEN
GW Visser, RP Klok, JWK Gebbinck… - Journal of Nuclear …, 2001 - Soc Nuclear Med
A novel, facile procedure for efficient coupling of high doses of 131 I to monoclonal
antibodies (MAbs) was developed with minimal chemical and radiation damage. Methods: To …
antibodies (MAbs) was developed with minimal chemical and radiation damage. Methods: To …
Proteomic screen identifies IGFBP7 as a novel component of endothelial cell-specific Weibel-Palade bodies
…, EL van Agtmaal, BS Dragt, JK Gebbinck… - Journal of proteome …, 2012 - ACS Publications
Vascular endothelial cells contain unique storage organelles, designated Weibel-Palade
bodies (WPBs), that deliver inflammatory and hemostatic mediators to the vascular lumen in …
bodies (WPBs), that deliver inflammatory and hemostatic mediators to the vascular lumen in …
Pertussis toxin inhibition of T-cell hybridoma invasion is reversed by manganese-induced activation of LFA-1
GL Rivière, JWTM Klein Gebbinck… - journal of Cell …, 1994 - journals.biologists.com
Pertussis toxin (PT) inhibits invasiveness of T-cell hybridomas in vitro and metastasis
formation in vivo. We present evidence for the hypothesis that PT interferes with functional …
formation in vivo. We present evidence for the hypothesis that PT interferes with functional …
A single lysine of the two-lysine recognition motif of the D3 domain of receptor-associated protein is sufficient to mediate endocytosis by low-density lipoprotein …
…, E Sellink, JWTMK Gebbinck… - The international journal …, 2011 - Elsevier
Ligand binding of the low-density lipoprotein (LDL) receptor family is mediated by complement-type
repeats (CR) each comprising a binding pocket for a single basic amino acid residue…
repeats (CR) each comprising a binding pocket for a single basic amino acid residue…
In vitro invasiveness of CTL clones and in vivo dissemination of CTL hybridomas
G La Rivière, JWTMK Gebbinck… - Journal of leukocyte …, 1993 - Wiley Online Library
Activated spleen T cells are invasive in hepatocyte and fibroblast cultures, and this property
is dominantly expressed in T cell hybridomas. The invasive potential of the hybrids …
is dominantly expressed in T cell hybridomas. The invasive potential of the hybrids …
Two-step purification of a murine monoclonal antibody intended for therapeutic application in man: Optimisation of purification conditions and scaling up
…, JJCC Van Hertrooij, JWTMK Gebbinck… - Journal of …, 1989 - Elsevier
… Wim Jiskoot 1, Jos JCC Van Hertrooij 2, Jacqueline WTM Klein Gebbinck 2 Tiny Van der …
prepared with 4% (w/v) acrylamide, running gels either with 6.25% or 12.5% (w/v) acrylamide, …
prepared with 4% (w/v) acrylamide, running gels either with 6.25% or 12.5% (w/v) acrylamide, …
Preparation of clinical grade monoclonal antibodies from serum-containing cell culture supernatants
…, AMV Hoven, JWTMK Gebbinck… - Journal of …, 1991 - Elsevier
… Hoven 2, Jacqueline WTM Klein Gebbinck 2 Tiny Van der Velden-de Groot z Daan JA Crommelin
a and E. Coen Beuvery 2 … JJCC, Klein Gebbinck, JWI".M.. Van der Velden-de Groot, T.. …
a and E. Coen Beuvery 2 … JJCC, Klein Gebbinck, JWI".M.. Van der Velden-de Groot, T.. …
Putative invasion‐specific proteins in mouse T‐cell hybridomas that differ in invasive and metastatic potential
…, CA Schipper, JWTM Klein Gebbinck… - … journal of cancer, 1992 - Wiley Online Library
Fusion of invasive, activated T‐lymphocytes with non‐invasive BW5147 T‐lymphoma cells
mainly yields highly invasive (HI), highly metastatic T‐cell hybridomas. In addition, several …
mainly yields highly invasive (HI), highly metastatic T‐cell hybridomas. In addition, several …
Cellular and humoral responses after multiple injections of unconjugated chimeric monoclonal antibody MOv18 in ovarian cancer patients: a pilot study
I van Zanten-Przybysz, C Molthoff, J Gebbinck… - Journal of cancer …, 2002 - Springer
… Iwona van Zanten-Przybysz Æ Carla Molthoff Jacqueline Klein Gebbinck Æ Silvia von
Mensdorff-… van Zanten-Przybysz Æ JK Gebbinck S. von Mensdorff-Pouilly Æ R. Verstraeten P. …
Mensdorff-… van Zanten-Przybysz Æ JK Gebbinck S. von Mensdorff-Pouilly Æ R. Verstraeten P. …
[PDF][PDF] Radioimmunotherapy with intravenously administered 131I-labeled chimeric monoclonal antibody MOv18 in patients with ovarian cancer
I van Zanten-Przybysz, CF Molthoff… - Journal of Nuclear …, 2000 - Soc Nuclear Med
… Wilhelm for assisting with the antibody infusion, Jacqueline W. Klein Gebbinck and Rob Klok
for technical assistance, Greet van Zanten and Marian Ouwens for outstanding patient care, …
for technical assistance, Greet van Zanten and Marian Ouwens for outstanding patient care, …