Imidazo[1,2-a]pyridines bearing a 3-(dithiolan-, dioxolan- or oxathiolan-2-yl) substituent were
synthesized from the corresponding aldehydes. The dithiolanyl derivative 6a proved active …

A series of imidazo[1,2-a]pyrrolo[2,3-c]pyridines has been prepared and evaluated for their
anti-BVDV activities in MDBK cells. From the synthesized analogues bearing modifications of …

Phthalic acid esters have been widely used to improve the plasticity of PVC medical devices.
They carry a high exposure risk for both humans and the environment in clinical situations. …

Targeted radionuclide therapy using radioiodinated compounds with a specific affinity for
melanoma tissue is a promising treatment for disseminated melanoma, but the candidate with …

Metastatic melanoma is one of the most aggressive forms of skin cancer and has a poor
prognosis. We have previously identified Annexin A1 (ANXA1) as a potential murine melanoma-…

It has been suggested that chemoresistance of chondrosarcoma (CHS), the cartilage tumor,
is caused by the phenotypic microenvironmental features of the tumor tissue, mainly the …

Rationale: Pretargeted radioimmunotherapy (PRIT) based upon bioorthogonal click chemistry
has been investigated for the first time in the context of peritoneal carcinomatosis using a …

Novel imidazo[1,2-a]naphthyridinic systems 6a–15a and 6b–15b were obtained from
Friedländer's reaction in imidazo[1,2-a]pyridine series. Most of the compounds were evaluated for …

In recent years, there has been dramatic worldwide increase in incidence of malignant
melanoma. Although localised disease is often curable by surgical excision, metastatic …

Tetraspanin 8 (TSPAN8) overexpression is correlated with poor prognosis in human colorectal
cancer (CRC). A murine mAb Ts29. 2 specific for human TSPAN8 provided significant …