In this review, evidence is provided that apolipoprotein E (apoE) genotype accounts for the
majority of Alzheimer’s disease (AD) risk and pathology. The three major human isoforms, …

The value of screening for cognitive impairment, including dementia and Alzheimer's disease,
has been debated for decades. Recent research on causes of and treatments for cognitive …

The risk of developing Alzheimer’s disease (AD) is tied most closely to age and appears to
follow Gompertzian kinetics. However, specific genetic factors are also linked closely to AD, …

This study describes the prevalence of violence and the putative risk factors for violence in
184 Alzheimer patients and their primary caregivers living in the community. Analysis of the …

We have previously reported anti-amyloidogenic effects of leptin using in vitro and in vivo
models and, more recently, demonstrated the ability of leptin to reduce tau phosphorylation in …

Extensive neuropathological studies have established a compelling link between abnormalities
in structure and function of subcortical monoaminergic (MA-ergic) systems and the …

OBJECTIVE: To describe the relationship of Mini‐Mental State Exam (MMSE) scores and
changes over time in MMSE scores to age and education in a population of older women. …

To develop a tool for precisely assessing dementia severity, items should be selected
according to their relationship to the overall progression of the disease. Using an item …

Soldiers with a traumatic brain injury (TBI) present with an array of neuropsychiatric symptoms
that can be grouped into nosological clusters:(1) cognitive dysfunctions: difficulties in …

COVID-19 is a severe infectious disease that has claimed> 150,000 lives and infected millions
in the United States thus far, especially the elderly population. Emerging evidence has …